ELISA/assay

Human GLP-2 (Glucagon Like Peptide 2) ELISA Kit

MBS2510411

48-Strip-Wells

410 USD

ELISA Kit

Human GLP-2 (Glucagon Like Peptide 2) ELISA Kit

GLP-2

glucagon-like peptide 2 receptor; Glucagon-like peptide 2 receptor; glucagon-like peptide 2 receptor; GLP-2 receptor; glucagon-like peptide 2 receptor

GLP-2

GLP2R; GLP2R; GLP-2 receptor; GLP-2-R; GLP-2R

GLP2R_HUMAN

Human

553

This kit recognizes natural and recombinant Human GLP-2. No significant cross-reactivity or interference between Human GLP-2 and analogues was observed.

Store at 4 degree C.

Samples: Serum, plasma and other biological fluids. Assay Type: Competitive. Detection Range: 0.156-10ng/mL. Sensitivity: 0.094ng/mL

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human GLP-2 concentrations in serum, plasma and other biological fluids. Principle of the Assay This ELISA kit uses Competitive-ELISA as the method. The microtiter plate provided in this kit has been pre-coated with GLP-2. During the reaction, GLP-2 in the sample or standard competes with a fixed amount of GLP-2 on the solid phase supporter for sites on the Biotinylated Detection Ab specific to GLP-2. Excess conjugate and unbound sample or standard are washed from the plate, and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of GLP-2 in the samples is then determined by comparing the OD of the samples to the standard curve.

4758438

NP_004237.1

NM_004246.2

O95838

63,001 Da

Class B/2 (Secretin Family Receptors) Pathway (106378); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class B Secretin-like Pathway (198781); Glucagon-type Ligand Receptors Pathway (106380); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Neuroactive Ligand-receptor Interaction Pathway (83053)

This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]

GLP2R: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family. Protein type: Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR. Chromosomal Location of Human Ortholog: 17p13.3. Cellular Component: plasma membrane; integral to membrane. Molecular Function: G-protein coupled receptor activity; glucagon receptor activity. Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; positive regulation of cell proliferation

48-Strip-Wells

410 USD

96-Strip-Wells

490