Rat LOX-1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) ELISA Kit | MyBioSource MBS2509888 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat LOX-1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) ELISA Kit

catalog :

MBS2509888

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2509888

products type :

ELISA Kit

products full name :

Rat LOX-1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) ELISA Kit

products short name :

[LOX-1]

other names :

[lectin-like oxidized low-density lipoprotein receptor; Oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; lectin-type oxidized LDL receptor 1; ox-LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; Lectin-like oxidized LDL receptor 1; LOX-1; Lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1Oxidized low-density lipoprotein receptor 1, soluble form]

products gene name :

[LOX-1]

other gene names :

[Olr1; Olr1; LOX-1; Oldr1; Oldlr1; Lox1; Oldlr1; Ox-LDL receptor 1; LOX-1; Lectin-like oxLDL receptor 1]

uniprot entry name :

OLR1_RAT

reactivity :

Rat

sequence length :

364

specificity :

This assay has high sensitivity and excellent specificity for detection of Rat LOX-1. No significant cross-reactivity or interference between Rat LOX-1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat LOX-1 and all the analogues, therefore, cross reaction may still exist.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.156-10ng/mL. Sensitivity: Min: 0.094ng/mL; Max: 10ng/mL

products description :

Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of LOX-1 in Rat serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat LOX-1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat LOX-1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat LOX-1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat LOX-1. You can calculate the concentration of Rat LOX-1 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4008187

ncbi acc num :

BAA35123.1

uniprot acc num :

O70156

ncbi mol weight :

41,890 Da

ncbi pathways :

Cell Surface Interactions At The Vascular Wall Pathway (1120553); Hemostasis Pathway (1120520); PPAR Signaling Pathway (83434); PPAR Signaling Pathway (450); Phagosome Pathway (153901); Phagosome Pathway (153859)

ncbi summary :

receptor for oxidized low-density lipoprotein that may be involved in pathogenesis of hypertension as well as atherosclerosis [RGD, Feb 2006]

uniprot summary :

Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590