ELISA/assay

Mouse TSLP (Thymic Stromal Lymphopoietin) ELISA Kit

MBS2509213

24-Strip-Wells

215 USD

ELISA Kit

Mouse TSLP (Thymic Stromal Lymphopoietin) ELISA Kit

[TSLP]

[thymic stromal lymphopoietin isoform 1; Thymic stromal lymphopoietin; thymic stromal lymphopoietin; thymic stromal lymphopoietin]

[TSLP]

[TSLP; TSLP]

TSLP_HUMAN

Mouse

159

This assay has high sensitivity and excellent specificity for detection of Mouse TSLP. No significant cross-reactivity or interference between Mouse TSLP and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse TSLP and all the analogues, therefore, cross reaction may still exist.

Store at 4 degree C.

Typical Testing Data/Standard Curve (for reference only)

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 15.625-1000pg/mL. Sensitivity: Min: 9.375pg/mL; Max: 1000pg/mL

Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of TSLP in Mouse serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse TSLP. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse TSLP and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse TSLP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse TSLP. You can calculate the concentration of Mouse TSLP in the samples by comparing the OD of the samples to the standard curve.

14719428

NP_149024.1

NM_033035.4

Q969D9

7,426 Da

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); TSLP Signaling Pathway (672451)

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

TSLP: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q22.1. Cellular Component: extracellular space. Molecular Function: cytokine activity

24-Strip-Wells

215 USD

48-Strip-Wells

410

96-Strip-Wells

490

5x96-Strip-Wells

2040

10x96-Strip-Wells

3590