catalog number :
MBS250915
products type :
Native Protein
products full name :
Native Advanced Glycation End Product (AGE)
products short name :
Native Advanced Glycation End Product (AGE)
sequence :
An advanced glycation end-product (AGE) is the result of a chain of chemical reactions after an initial glycation reaction. Glycation is accomplished by the Maillard reaction, which is a multistep process that begins with Schiff base formation between the amine and the carbonyl group on the sugar followed by rearrangement to form Amadori intermediates. AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases. They are also believed to play a causative role in the vascular complications of diabetes mellitus
form :
Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 Degree C for one month. Aliquot and store at -80 Degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 Degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE; WB; ELISA; IP. (May be suitable for use in other assays to be determined by the end user.)
other info1 :
Endotoxin Level: <1.0EU per 1?g (determined by the LAL method). Usage: Reconstitute in ddH2O.
other info2 :
Organism Species: General
products description :
An advanced glycation end-product (AGE) is the result of a chain of chemical reactions after an initial glycation reaction. Glycation is accomplished by the Maillard reaction, which is a multistep process that begins with Schiff base formation between the amine and the carbonyl group on the sugar followed by rearrangement to form Amadori intermediates. AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases. BSA is glycosylated by the reaction of the glucose and BSA in vitro, and then being multistep purification, ending in high puified AGEs.