catalog number :
MBS2508952
products type :
ELISA Kit
products full name :
Human MCP/CD46(Membrane Cofactor Protein)ELISA Kit
products short name :
MCP/CD46
other names :
membrane cofactor protein; Membrane cofactor protein; membrane cofactor protein; CD46 antigen, complement regulatory protein; CD46 molecule, complement regulatory protein; CD_antigen: CD46
products gene name :
MCP/CD46
other gene names :
Cd46; Cd46; Mcp; Mcp
uniprot entry name :
MCP_RAT
specificity :
This assay has high sensitivity and excellent specificity for detection of Human MCP/CD46. No significant cross-reactivity or interference between Human MCP/CD46 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human MCP/CD46 and all the analogues, therefore, cross reaction may still exist.
storage stability :
Store at 4 degree C.
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 7.813--500pg/mL. Sensitivity: 4.688pg/mL
products description :
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of MCP/CD46 in human serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human MCP/CD46. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human MCP/CD46 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human MCP/CD46, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human MCP/CD46. You can calculate the concentration of Human MCP/CD46 in the samples by comparing the OD of the samples to the standard curve.
ncbi acc num :
NP_062063.1
ncbi gb acc num :
NM_019190.1
ncbi mol weight :
39,787 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway (198461); Complement And Coagulation Cascades Pathway (83465); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (1121571); Immune System Pathway (1121507); Innate Immune System Pathway (1121536); Measles Pathway (213300); Measles Pathway (213277); Regulation Of Complement Cascade Pathway (1121580)
ncbi summary :
may be involved in fertilization or reproduction; human homolog acts as an inhibitor of plasma membrane complement [RGD, Feb 2006]