Porcine OxLDL (Oxidized Low Density Lipoprotein) ELISA Kit | MyBioSource MBS2508909 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Porcine OxLDL (Oxidized Low Density Lipoprotein) ELISA Kit

catalog :

MBS2508909

quantity :

24-Strip-Wells

price :

210 USD

product information

catalog number :

MBS2508909

products type :

ELISA Kit

products full name :

Porcine OxLDL (Oxidized Low Density Lipoprotein) ELISA Kit

products short name :

[OxLDL]

other names :

[oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; BLOX1; LOX-1; bLOX-1; lectin-like oxLDL receptor 1; lectin-like oxidized LDL receptor 1; lectin-type oxidized LDL receptor 1; ox-LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1<; Lectin-like oxidized LDL receptor 1; LOX-1; Lectin-like oxLDL receptor 1; bLOX-1; Lectin-type oxidized LDL receptor 1Cleaved into the following 2 chains:Oxidized low-density lipoprotein receptor 1, soluble form A; Oxidized low-density lipoprotein receptor 1, soluble form B]

products gene name :

[OxLDL]

other gene names :

[OLR1; OLR1; LOX1; Ox-LDL receptor 1; LOX-1; Lectin-like oxLDL receptor 1; bLOX-1]

uniprot entry name :

OLR1_BOVIN

reactivity :

Porcine

sequence length :

270

specificity :

This kit recognizes natural and recombinantPorcineOxLDL. No significant cross-reactivity or interference between PorcineOxLDL and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 1.563-100nmol/mL. Sensitivity: Min: 0.938nmol/mL; Max: 100nmol/mL

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of PorcineOxLDLconcentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to OxLDL. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for OxLDLand Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain OxLDL, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of OxLDL.You can calculate the concentration of OxLDLin the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

27806503

ncbi acc num :

NP_776557.1

ncbi gb acc num :

NM_174132.2

uniprot acc num :

P79391

ncbi mol weight :

30,892 Da

ncbi pathways :

Cell Surface Interactions At The Vascular Wall Pathway (1120420); Hemostasis Pathway (1120392); PPAR Signaling Pathway (84281); PPAR Signaling Pathway (450); Phagosome Pathway (153904); Phagosome Pathway (153859)

uniprot summary :

Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.

size1 :

24-Strip-Wells

price1 :

210 USD

size2 :

48-Strip-Wells

price2 :

400

size3 :

96-Strip-Wells

price3 :

475

size4 :

5x96-Strip-Wells

price4 :

1975

size5 :

10x96-Strip-Wells

price5 :

3480