Rat VEGF-D (Vascular Endothelial Cell Growth Factor D) ELISA Kit | MyBioSource MBS2508749 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat VEGF-D (Vascular Endothelial Cell Growth Factor D) ELISA Kit

catalog :

MBS2508749

quantity :

24-Strip-Wells

price :

190 USD

product information

catalog number :

MBS2508749

products type :

ELISA Kit

products full name :

Rat VEGF-D (Vascular Endothelial Cell Growth Factor D) ELISA Kit

products short name :

[VEGF-D]

other names :

[vascular endothelial growth factor D preproprotein; Vascular endothelial growth factor D; vascular endothelial growth factor D; c-fos induced growth factor (vascular endothelial growth factor D); c-Fos-induced growth factor; FIGF]

products gene name :

[VEGF-D]

other gene names :

[FIGF; FIGF; VEGFD; VEGF-D; VEGFD; VEGF-D; FIGF]

uniprot entry name :

VEGFD_HUMAN

reactivity :

Rat

sequence length :

354

specificity :

This kit recognizes natural and recombinant Rat VEGF-D. No significant cross-reactivity or interference between Rat VEGF-D and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 15.625-1000pg/mL. Sensitivity: Min: 9.375pg/mL; Max: 1000pg/mL

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rat VEGF-D concentrations in serum, plasma and other biological fluids. Principle of the Assay This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to VEGF-D. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for VEGF-D and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain VEGF-D, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of VEGF-D. You can calculate the concentration of VEGF-D in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4758378

ncbi acc num :

NP_004460.1

ncbi gb acc num :

NM_004469.4

uniprot acc num :

O43915

ncbi mol weight :

40,444 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); Hemostasis Pathway (106028); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979); Pathways In Cancer (83105); Platelet Activation, Signaling And Aggregation Pathway (106034)

ncbi summary :

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]

uniprot summary :

VEGFD: Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Belongs to the PDGF/VEGF growth factor family. Protein type: Secreted, signal peptide; Cytokine; Motility/polarity/chemotaxis; Secreted. Chromosomal Location of Human Ortholog: Xp22.31. Cellular Component: extracellular space; membrane; extracellular region. Molecular Function: protein homodimerization activity; growth factor activity; platelet-derived growth factor receptor binding; vascular endothelial growth factor receptor 3 binding; vascular endothelial growth factor receptor binding; chemoattractant activity. Biological Process: platelet activation; cell proliferation; platelet degranulation; positive chemotaxis; positive regulation of cell division; positive regulation of cell proliferation; angiogenesis; vascular endothelial growth factor receptor signaling pathway; blood coagulation; cell differentiation; induction of positive chemotaxis

size1 :

24-Strip-Wells

price1 :

190 USD

size2 :

48-Strip-Wells

price2 :

310

size3 :

96-Strip-Wells

price3 :

355

size4 :

5x96-Strip-Wells

price4 :

1435

size5 :

10x96-Strip-Wells

price5 :

2805