Mouse PTGES (Prostaglandin E Synthase, Microsomal) ELISA Kit | MyBioSource MBS2507178 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse PTGES (Prostaglandin E Synthase, Microsomal) ELISA Kit

catalog :

MBS2507178

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2507178

products type :

ELISA Kit

products full name :

Mouse PTGES (Prostaglandin E Synthase, Microsomal) ELISA Kit

products short name :

[PTGES]

other names :

[prostaglandin E synthase; Prostaglandin E synthase; prostaglandin E synthase; MGST1-like 1; glutathione S-transferase 1-like 1; microsomal glutathione S-transferase 1-like 1; microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; tumor protein p53 inducible protein 12; prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein]

products gene name :

[PTGES]

other gene names :

[PTGES; PTGES; PGES; MPGES; PIG12; PP102; PP1294; MGST-IV; MGST1L1; TP53I12; mPGES-1; MGST1-L1; MGST1L1; MPGES1; PGES; PIG12; MGST1-L1; MPGES-1]

uniprot entry name :

PTGES_HUMAN

reactivity :

Mouse

sequence length :

152

specificity :

This kit recognizes Mouse CNTF in samples. No s ignificant cross-reactivity or interference between Mouse CNTF and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 39.06-2500pg/mL. Sensitivity: 23.44 pg/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, midrange and high level Mouse CNTF were tested 20times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, midrange and high level Mouse CNTF were testedon 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of Mouse CNTF concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse CNTF. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse CNTF and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse CNTF, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-subst rate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse CNTF. You can calculate the concentration of Mouse CNTF in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4758910

ncbi acc num :

NP_004869.1

ncbi gb acc num :

NM_004878.4

uniprot acc num :

O14684

ncbi mol weight :

17,102 Da

ncbi pathways :

Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); Eicosanoid Synthesis Pathway (198888); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Synthesis Of Prostaglandins (PG) And Thromboxanes (TX) Pathway (730333)

ncbi summary :

The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]

uniprot summary :

PTGES: Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Belongs to the MAPEG family. Protein type: Isomerase; Membrane protein, integral; EC 5.3.99.3; Membrane protein, multi-pass; Lipid Metabolism - arachidonic acid; Nuclear envelope. Chromosomal Location of Human Ortholog: 9q34.3. Cellular Component: endoplasmic reticulum membrane; membrane; perinuclear region of cytoplasm; nuclear envelope lumen; integral to membrane. Molecular Function: glutathione binding; prostaglandin-E synthase activity. Biological Process: negative regulation of cell proliferation; chronic inflammatory response; response to retinoic acid; response to cytokine stimulus; cyclooxygenase pathway; arachidonic acid metabolic process; response to lipopolysaccharide; prostaglandin biosynthetic process; signal transduction; response to calcium ion; response to organic cyclic substance; acute inflammatory response; prostaglandin metabolic process

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590