This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat IL-12 (Interleukin 12) ELISA Kit
catalog :
MBS2507061
quantity :
24-Strip-Wells
price :
190 USD
product information
catalog number :
MBS2507061
products type :
ELISA Kit
products full name :
Rat IL-12 (Interleukin 12) ELISA Kit
products short name :
[IL-12]
other names :
[Il-12 receptor beta2; Interleukin-12 receptor subunit beta-2; interleukin-12 receptor subunit beta-2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; interleukin-12 receptor beta-2 chain; interleukin 12 receptor, beta 2]
products gene name :
[IL-12]
other gene names :
[IL12RB2; IL12RB2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2]
uniprot entry name :
I12R2_HUMAN
reactivity :
Rat
sequence length :
862
specificity :
This kit recognizes Rat IL-12 in samples. No Significant cross-reactivity or interference between Rat IL-12 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 15.625-1000pg/mL. Sensitivity: Min: 9.375pg/mL; Max: 1000pg/mL
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Rat IL-12 were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Rat IL-12 were tested on 3 different plates, 20 replicates in each plate.
products description :
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rat IL-12 concentrations in serum, plasma and other biological fluids.
ncbi gi num :
1685028
ncbi acc num :
AAB36675.1
uniprot acc num :
Q99665
ncbi mol weight :
87,484 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL12-mediated Signaling Events Pathway (137922); IL27-mediated Signaling Events Pathway (137929); Inflammatory Bowel Disease (IBD) Pathway (842771); Inflammatory Bowel Disease (IBD) Pathway (842797); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488)
ncbi summary :
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
uniprot summary :
IL12RB2: Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. Belongs to the type I cytokine receptor family. Type 2 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, cytokine; Cell cycle regulation. Chromosomal Location of Human Ortholog: 1p31.3-p31.2. Cellular Component: integral to plasma membrane; external side of plasma membrane. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein kinase binding. Biological Process: positive regulation of interferon-gamma production; peptidyl-tyrosine phosphorylation; cell surface receptor linked signal transduction; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; interferon-gamma production; response to lipopolysaccharide
size1 :
24-Strip-Wells
price1 :
190 USD
size2 :
48-Strip-Wells
price2 :
310
size3 :
96-Strip-Wells
price3 :
355
size4 :
5x96-Strip-Wells
price4 :
1435
size5 :
10x96-Strip-Wells
price5 :
2805
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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