This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human CMLC-1 (Cardiac Myosin Light Chains 1) ELISA Kit
catalog :
MBS2506936
quantity :
24-Strip-Wells
price :
215 USD
product information
catalog number :
MBS2506936
products type :
ELISA Kit
products full name :
Human CMLC-1 (Cardiac Myosin Light Chains 1) ELISA Kit
products short name :
[CMLC-1]
other names :
[cardiac myosin light chain-1; Myosin light chain 3; myosin light chain 3; CMLC1; cardiac myosin light chain 1; myosin light chain 1, slow-twitch muscle B/ventricular isoform; myosin, light polypeptide 3, alkali; ventricular, skeletal, slow; ventricular/slow twitch myosin alkali light chain; myosin, light chain 3, alkali; ventricular, skeletal, slow; Cardiac myosin light chain 1; CMLC1; Myosin light chain 1, slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain]
products gene name :
[CMLC-1]
other gene names :
[MYL3; MYL3; CMH8; VLC1; MLC1V; MLC1SB; CMLC1; MLC1SB]
uniprot entry name :
MYL3_HUMAN
reactivity :
Human
sequence length :
195
specificity :
This kit recognizes Human CMLC-1 in samples. No Significant cross-reactivity or interference between Human CMLC-1 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.625-40ng/mL. Sensitivity: Min: 0.375ng/mL; Max: 40ng/mL
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human CMLC-1 were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human CMLC-1 were tested on 3 different plates, 20 replicates in each plate.
products description :
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human CMLC-1 concentrations in serum, plasma and other biological fluids.
ncbi gi num :
9651188
ncbi acc num :
AAF91089.1
uniprot acc num :
P08590
ncbi mol weight :
21,932 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Cardiac Muscle Contraction Pathway (93344); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114229); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Muscle Contraction Pathway (106261); Regulation Of Actin Cytoskeleton Pathway (198874)
ncbi summary :
MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
uniprot summary :
MYL3: Regulatory light chain of myosin. Does not bind calcium. Defects in MYL3 are the cause of familial hypertrophic cardiomyopathy type 8 (CMH8). Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. CMH8 inheritance can be autosomal dominant or recessive. Protein type: Motor; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 3p21.3-p21.2. Cellular Component: I band; sarcomere; muscle myosin complex; cytosol; A band. Molecular Function: actin monomer binding; structural constituent of muscle; motor activity; myosin II heavy chain binding; calcium ion binding. Biological Process: skeletal muscle development; metabolic process; positive regulation of ATPase activity; regulation of striated muscle contraction; ventricular cardiac muscle morphogenesis; regulation of the force of heart contraction; muscle filament sliding; cardiac muscle contraction. Disease: Cardiomyopathy, Familial Hypertrophic, 8
size1 :
24-Strip-Wells
price1 :
215 USD
size2 :
48-Strip-Wells
price2 :
410
size3 :
96-Strip-Wells
price3 :
490
size4 :
5x96-Strip-Wells
price4 :
2040
size5 :
10x96-Strip-Wells
price5 :
3590
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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