Mouse ASGR1 (Asialoglycoprotein Receptor 1) ELISA Kit | MyBioSource MBS2506807 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse ASGR1 (Asialoglycoprotein Receptor 1) ELISA Kit

catalog :

MBS2506807

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2506807

products type :

ELISA Kit

products full name :

Mouse ASGR1 (Asialoglycoprotein Receptor 1) ELISA Kit

products short name :

[ASGR1]

other names :

[asialoglycoprotein receptor 1 isoform b; Asialoglycoprotein receptor 1; asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; hepatic lectin H1; asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; Hepatic lectin H1; HL-1]

products gene name :

[ASGR1]

other gene names :

[ASGR1; ASGR1; HL-1; ASGPR; ASGPR1; CLEC4H1; CLEC4H1; ASGP-R 1; ASGPR 1; HL-1]

uniprot entry name :

ASGR1_HUMAN

reactivity :

Mouse

sequence length :

252

specificity :

This kit recognizes natural and recombinantMouseASGR1. No significant cross-reactivity or interference between MouseASGR1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 31.25-2000pg/mL. Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of MouseASGR1concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to ASGR1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for ASGR1and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain ASGR1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of ASGR1.You can calculate the concentration of ASGR1in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

308387363

ncbi acc num :

NP_001184145.1

ncbi gb acc num :

NM_001197216.2

uniprot acc num :

P07306

ncbi mol weight :

29,144 Da

ncbi pathways :

Thyroid Hormone Synthesis Pathway (835410); Thyroid Hormone Synthesis Pathway (839541)

ncbi summary :

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

uniprot summary :

ASGR1: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13.2. Cellular Component: integral to plasma membrane; extracellular region. Molecular Function: protein binding; protein homodimerization activity; metal ion binding; asialoglycoprotein receptor activity; carbohydrate binding. Biological Process: receptor-mediated endocytosis; cellular response to extracellular stimulus

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590