Porcine CLDN4 (Claudin 4) ELISA Kit | MyBioSource MBS2506467 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Porcine CLDN4 (Claudin 4) ELISA Kit

catalog :

MBS2506467

quantity :

24-Strip-Wells

price :

235 USD

product information

catalog number :

MBS2506467

products type :

ELISA Kit

products full name :

Porcine CLDN4 (Claudin 4) ELISA Kit

products short name :

[CLDN4]

other names :

[claudin-4; Claudin-4; claudin-4; CPE-receptor; Clostridium perfringens enterotoxin receptor 1; Williams-Beuren syndrome chromosomal region 8 protein; claudin 4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein]

products gene name :

[CLDN4]

other gene names :

[CLDN4; CLDN4; CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; CPER; CPETR1; WBSCR8; CPE-R; CPE-receptor]

uniprot entry name :

CLD4_HUMAN

reactivity :

Porcine

sequence length :

209

specificity :

This kit recognizes natural and recombinantPorcineCLDN4. No significant cross-reactivity or interference between PorcineCLDN4 and analogues was observed.

storage stability :

Store at 4 degree C.

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 78.125-5000pg/mL. Sensitivity: Min: 46.875pg/mL; Max: 5000pg/mL

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of PorcineCLDN4concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to CLDN4. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for CLDN4and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain CLDN4, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of CLDN4.You can calculate the concentration of CLDN4in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4502877

ncbi acc num :

NP_001296.1

ncbi gb acc num :

NM_001305.4

uniprot acc num :

O14493

ncbi mol weight :

22,077 Da

ncbi pathways :

Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Tight Junction Pathway (83071)

ncbi summary :

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]

uniprot summary :

Claudin-4: Plays a major role in tight junction-specific obliteration of the intercellular space. CLDN4 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the claudin family. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cytoskeletal. Chromosomal Location of Human Ortholog: 7q11.23. Cellular Component: tight junction; integral to plasma membrane; apicolateral plasma membrane; apical plasma membrane; basal plasma membrane; plasma membrane; lateral plasma membrane. Molecular Function: identical protein binding; transmembrane receptor activity; structural molecule activity. Biological Process: female pregnancy; response to progesterone stimulus; signal transduction; calcium-independent cell-cell adhesion

size1 :

24-Strip-Wells

price1 :

235 USD

size2 :

48-Strip-Wells

price2 :

450

size3 :

96-Strip-Wells

price3 :

535

size4 :

5x96-Strip-Wells

price4 :

2255

size5 :

10x96-Strip-Wells

price5 :

3975