catalog number :
MBS2506210
products type :
ELISA Kit
products full name :
Human PAI2 (Plasminogen Activator Inhibitor 2)ELISA Kit
products short name :
[PAI2]
other names :
[plasminogen activator inhibitor 2; Plasminogen activator inhibitor 2; plasminogen activator inhibitor 2; monocyte Arg-serpin; placental plasminogen activator inhibitor; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; serpin B2; urokinase inhibitor; serpin peptidase inhibitor, clade B (ovalbumin), member 2; Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor]
products gene name :
[PAI2]
other gene names :
[SERPINB2; SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201; PAI2; PLANH2; PAI-2]
uniprot entry name :
PAI2_HUMAN
specificity :
This kit recognizes natural and recombinant Human PAI2. No significant cross-reactivity or interference between Human PAI2 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 1.563-100ng/mL. Sensitivity: Min: 0.938ng/mL; Max: 100ng/mL
products description :
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human PAI2 concentrations in serum, plasma and other biological fluids. Principle of the Assay This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to PAI2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PAI2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PAI2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of PAI2. You can calculate the concentration of PAI2 in the samples by comparing the OD of the samples to the standard curve.
ncbi acc num :
NP_001137290.1
ncbi gb acc num :
NM_001143818.1
ncbi mol weight :
46,596 Da
ncbi pathways :
Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Blood Clotting Cascade Pathway (198840); Dissolution Of Fibrin Clot Pathway (106061); Hemostasis Pathway (106028); Senescence And Autophagy Pathway (198780)
uniprot summary :
SERPINB2: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. Belongs to the serpin family. Ov-serpin subfamily. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 18q21.3. Cellular Component: extracellular space; cytoplasm; plasma membrane; extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity. Biological Process: fibrinolysis; blood coagulation; negative regulation of apoptosis
size5 :
10x96-Strip-Wells