Mouse STAT2 (Signal Transducer And Activator Of Transcription 2) ELISA Kit | MyBioSource MBS2504928 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse STAT2 (Signal Transducer And Activator Of Transcription 2) ELISA Kit

catalog :

MBS2504928

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2504928

products type :

ELISA Kit

products full name :

Mouse STAT2 (Signal Transducer And Activator Of Transcription 2) ELISA Kit

products short name :

[STAT2]

other names :

[Stat2; Signal transducer and activator of transcription 2; signal transducer and activator of transcription 2; interferon alpha induced transcriptional activator; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2, 113kDa; p113]

products gene name :

[STAT2]

other gene names :

[STAT2; STAT2; P113; ISGF-3; STAT113]

uniprot entry name :

STAT2_HUMAN

reactivity :

Mouse

sequence length :

851

specificity :

This kit recognizes natural and recombinant Mouse STAT2. No significant cross-reactivity or interference between Mouse STAT2 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.625-40ng/mL. Sensitivity: Min: 0.375ng/mL; Max: 40ng/mL

other info2 :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Mouse STAT2 concentrations in serum, plasma and other biological fluids.

products description :

Principle of the assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to STAT2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for STAT2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain STAT2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of STAT2. You can calculate the concentration of STAT2 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

1293920

ncbi acc num :

AAA98760.1

uniprot acc num :

P52630

ncbi mol weight :

97,457 Da

ncbi pathways :

Adipogenesis Pathway (198832); CXCR4-mediated Signaling Events Pathway (137910); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Cytokine Signaling In Immune System Pathway (366171); EGFR1 Signaling Pathway (198782); Hepatitis B Pathway (694606); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Herpes Simplex Infection Pathway (377873)

ncbi summary :

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

uniprot summary :

STAT2: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Binds to the IFN-stimulated response element (ISRE) and to the Gas element. This multiprotein transcription factor is termed ISGF3. Two alternatively spliced isoforms have been described. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 12q13.3. Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol. Molecular Function: identical protein binding; protein binding; signal transducer activity; DNA binding; transcription factor activity. Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral reproduction; cytokine and chemokine mediated signaling pathway; JAK-STAT cascade; defense response to virus

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590