catalog number :
MBS250472
products type :
Recombinant Protein
products full name :
Somatostatin (SST)
products short name :
Somatostatin (SST)
other names :
Somatostatin; Somatostatin; somatostatin; somatostatin-14; somatostatin-28; prepro-somatostatin; growth hormone release-inhibiting factor; somatostatin; Growth hormone release-inhibiting factorCleaved into the following 2 chains:Somatostatin-28; Somatostatin-14
other gene names :
SST; SST; SMST; N/A
uniprot entry name :
SMS_HUMAN
sequence :
MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF- MLSCRLQCAL AALSIVLALG CVTGAPSDPR LRQFLQKSLA AAAGKQELAK YFLAELLSEP NQTENDALEP EDLSQAAEQD EMRLELQRSA NSNPAMAPRE RKAGCKNFFW KTFTSC
form :
Supplied as lyophilized form in 20mM Tris, 150mM NaCI, pH8.0, containing lmM EDTA, 1mM DT, 0.1% sarcosyl, 5% trehalose, and preservative.
storage stability :
Store at 2-8 degree C for one month; for long term storage, store at -20 degree C or -80 degree C
tested application :
SDS-PAGE; WB; ELISA; IP.
other info1 :
Tag Information: two N-terminal Tags, His-tag and S-tag. Residues: Metl ~Cys16. Accession #: P6127S . Endotoxin Level: Reconstitute in sterile PBS, pH7.2-ph7.4.
other info2 :
Organism: Homo sapiens (Human). Actual Mol. Mass : 25kOa as determined by SOS-PAGE reducing conditions. Note: Actual band size may differ from predicted due to:. - splice variants: Alternative splicing may create different sized proteins from the same
gene. -Relative charge: The composition of amino acids may affect the charge of the protein. - Post-translational modification: Phosphorylation, glycosylation, methylation, etc. -Post-translational cleavage: Many proteins are synthesized as pro-proteins, and then
cleaved to give the active form. -Polymerization of the target protein: Oimerization, multimerization, etc.
ncbi acc num :
AAH32625.1
ncbi mol weight :
18.4kDa
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Gastric Acid Secretion Pathway 154409!!Gastric Acid Secretion Pathway 154383!!Peptide Ligand-binding Receptors Pathway 106358!!SIDS Susceptibility Pathways 198901!!Signal Transduction Pathway 477114!!Signaling By GPCR Pathway 106356
ncbi summary :
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]