ELISA/assay

Human PLTP(Phospholipid Transfer Protein)ELISA Kit

MBS2503738

48-Strip-Wells

410 USD

ELISA Kit

Human PLTP(Phospholipid Transfer Protein)ELISA Kit

PLTP

phospholipid transfer protein isoform d; Phospholipid transfer protein; phospholipid transfer protein; BPI fold containing family E; lipid transfer protein II; phospholipid transfer protein; Lipid transfer protein II

PLTP

PLTP; PLTP; BPIFE; HDLCQ9

PLTP_HUMAN

Human

405

This kit recognizes natural and recombinant Human PLTP. No significant cross-reactivity or interference between Human PLTP and analogues was observed.

Store at 4 degree C.

Samples: Serum, plasma and other biological fluids. Assay Type: Sandwich. Detection Range: 0.313-20ng/mL. Sensitivity: The minimum detectable dose of Human PLTP is 0.188ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero).

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human PLTP concentrations in serum, plasma and other biological fluids.

Principle of the assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to PLTP. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PLTP and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PLTP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of PLTP. You can calculate the concentration of PLTP in the samples by comparing the OD of the samples to the standard curve.

339275810

NP_001229850.1

NM_001242921.1

P55058

44,847 Da

HDL-mediated Lipid Transport Pathway (106158); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Statin Pathway (198852)

The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

PLTP: Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid-binding; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 20q13.12. Cellular Component: extracellular space; extracellular region. Molecular Function: lipid binding. Biological Process: sperm motility; vitamin E biosynthetic process; lipid metabolic process; lipid transport

48-Strip-Wells

410 USD

96-Strip-Wells

490