Mouse VEGF-C (Vascular Endothelial cell Growth Factor C) ELISA Kit | MyBioSource MBS2503462 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse VEGF-C (Vascular Endothelial cell Growth Factor C) ELISA Kit

catalog :

MBS2503462

quantity :

24-Strip-Wells

price :

190 USD

product information

catalog number :

MBS2503462

products type :

ELISA Kit

products full name :

Mouse VEGF-C (Vascular Endothelial cell Growth Factor C) ELISA Kit

products short name :

[VEGF-C]

other names :

[vascular endothelial growth factor C preproprotein; Vascular endothelial growth factor C; vascular endothelial growth factor C; FLT4 ligand DHM; vascular endothelial growth factor-related protein; vascular endothelial growth factor C; Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein; VRP]

products gene name :

[VEGF-C]

other gene names :

[VEGFC; VEGFC; VRP; Flt4-L; LMPH1D; VEGF-C; Flt4-L; VRP]

uniprot entry name :

VEGFC_HUMAN

reactivity :

Mouse

sequence length :

419

specificity :

This kit recognizes Mouse VAP-1 in samples. No significant cross-reactivity or interference between Mouse VAP-1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 0.16-10ng/mL. Sensitivity: 0.1ng/mL

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Mouse VAP-1 were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Mouse VAP-1 were tested on 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Mouse VAP-1 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse VAP-1. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse VAP-1 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse VAP-1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse VAP-1. You can calculate the concentration of Mouse VAP-1 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4885653

ncbi acc num :

NP_005420.1

ncbi gb acc num :

NM_005429.4

uniprot acc num :

P49767

ncbi mol weight :

46,883 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); Heart Development Pathway (198802); Hemostasis Pathway (106028); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979); Pathways In Cancer (83105)

ncbi summary :

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]

uniprot summary :

VEGFC: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Homodimer; non-covalent and antiparallel. Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Belongs to the PDGF/VEGF growth factor family. Protein type: Cytokine; Secreted, signal peptide; Motility/polarity/chemotaxis; Cell cycle regulation; Secreted. Chromosomal Location of Human Ortholog: 4q34.3. Cellular Component: extracellular space; membrane; extracellular region. Molecular Function: protein binding; growth factor activity; vascular endothelial growth factor receptor 3 binding; chemoattractant activity. Biological Process: signal transduction; induction of positive chemotaxis; negative regulation of cell proliferation; morphogenesis of embryonic epithelium; platelet degranulation; positive chemotaxis; regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of cell proliferation; angiogenesis; negative regulation of blood pressure; positive regulation of cell-matrix adhesion; substrate-bound cell migration; response to drug; platelet activation; positive regulation of neuroblast proliferation; positive regulation of blood vessel endothelial cell migration; positive regulation of protein amino acid autophosphorylation; positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; organ morphogenesis; positive regulation of protein secretion; positive regulation of cell division; vascular endothelial growth factor receptor signaling pathway; blood coagulation; positive regulation of epithelial cell proliferation. Disease: Lymphedema, Hereditary, Id

size1 :

24-Strip-Wells

price1 :

190 USD

size2 :

48-Strip-Wells

price2 :

310

size3 :

96-Strip-Wells

price3 :

355

size4 :

5x96-Strip-Wells

price4 :

1435

size5 :

10x96-Strip-Wells

price5 :

2805