Human TDGF1 (Teratocarcinoma Derived Growth Factor 1) ELISA Kit | MyBioSource MBS2503395 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human TDGF1 (Teratocarcinoma Derived Growth Factor 1) ELISA Kit

catalog :

MBS2503395

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2503395

products type :

ELISA Kit

products full name :

Human TDGF1 (Teratocarcinoma Derived Growth Factor 1) ELISA Kit

products short name :

[TDGF1]

other names :

[teratocarcinoma-derived growth factor 1 isoform 1; Teratocarcinoma-derived growth factor 1; teratocarcinoma-derived growth factor 1; cripto-1 growth factor; epidermal growth factor-like cripto protein CR1; teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1]

products gene name :

[TDGF1]

other gene names :

[TDGF1; TDGF1; CR; CRGF; CRIPTO; CRIPTO; CRGF]

uniprot entry name :

TDGF1_HUMAN

reactivity :

Human

sequence length :

188

specificity :

This kit recognizes natural and recombinant Human TDGF1. No significant cross-reactivity or interference between Human TDGF1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.156-10ng/mL. Sensitivity: Min: 0.094ng/mL; Max: 10ng/mL

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human TDGF1 concentrations in serum, plasma and other biological fluids. Principle of the Assay This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to TDGF1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for TDGF1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain TDGF1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of TDGF1. You can calculate the concentration of TDGF1 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4507425

ncbi acc num :

NP_003203.1

ncbi gb acc num :

NM_003212.3

uniprot acc num :

P13385

ncbi mol weight :

21,169 Da

ncbi pathways :

Developmental Biology Pathway (477129); Glypican 1 Network Pathway (138010); POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway (1127697); Regulation Of Signaling By NODAL Pathway (477131); Signaling By NODAL Pathway (477130); Transcriptional Regulation Of Pluripotent Stem Cells Pathway (1127696)

ncbi summary :

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

uniprot summary :

TDGF1: Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Interacts with the activin type-1 receptor ACVR1B. Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung. Protein type: Membrane protein, peripheral; Motility/polarity/chemotaxis; Cell adhesion; Cell cycle regulation; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: extrinsic to plasma membrane; Golgi apparatus; extracellular space; cell surface; perinuclear region of cytoplasm; apical plasma membrane; plasma membrane; nucleus; lipid raft. Molecular Function: protein binding; growth factor activity; receptor binding. Biological Process: somatic stem cell maintenance; activation of MAPK activity; heart development; regulation of signal transduction; gastrulation; Wnt receptor signaling pathway through beta-catenin; cardiac muscle cell differentiation; BMP signaling pathway; positive regulation of fibroblast proliferation; mammary gland development; determination of anterior/posterior axis, embryo; positive regulation of cell proliferation; vasculogenesis; positive regulation of cell-matrix adhesion; cell differentiation; epidermal growth factor receptor signaling pathway; in utero embryonic development; morphogenesis of a branching structure; positive regulation of peptidyl-tyrosine phosphorylation; embryonic development; peptidyl-serine phosphorylation; cell migration during sprouting angiogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell migration; negative regulation of apoptosis

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590