catalog number :
MBS2503087
products type :
ELISA Kit
products full name :
Rat LRP-1 (Low-Density Lipoprotein-Receptor-Related Protein) ELISA Kit
products short name :
[LRP-1]
other names :
[low-density lipoprotein receptor-related protein 1; Low-density lipoprotein receptor-related protein 1; low-density lipoprotein receptor-related protein 1; alpha-2-macroglobulin receptor; prolow-density lipoprotein receptor-related protein 1; low density lipoprotein receptor-related protein 1; Alpha-2-macroglobulin receptor; A2MR]
products gene name :
[LRP-1]
other gene names :
[LRP1; LRP1; A2MR; LRP-1; LRP-1; A2MR]
uniprot entry name :
LRP1_CHICK
specificity :
This kit recognizes natural and recombinant Rat LRP-1. No significant cross-reactivity or interference between Rat LRP-1 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.625-40ng/mL. Sensitivity: Min: 0.375ng/mL; Max: 40ng/mL
products description :
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rat LRP-1 concentrations in serum, plasma and other biological fluids. Principle of the Assay This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to LRP-1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for LRP-1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain LRP-1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of LRP-1. You can calculate the concentration of LRP-1 in the samples by comparing the OD of the samples to the standard curve.
ncbi acc num :
NP_990573.1
ncbi gb acc num :
NM_205242.1
ncbi mol weight :
506,631 Da
uniprot summary :
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors.
size5 :
10x96-Strip-Wells