This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human FcalphaR/CD89 (Receptor I for the Fc Fragment of IgA) ELISA Kit
catalog :
MBS2502432
quantity :
24-Strip-Wells
price :
215 USD
product information
catalog number :
MBS2502432
products type :
ELISA Kit
products full name :
Human FcalphaR/CD89 (Receptor I for the Fc Fragment of IgA) ELISA Kit
products short name :
[FcalphaR/CD89]
other names :
[Fc alpha receptor; Immunoglobulin alpha Fc receptor; immunoglobulin alpha Fc receptor; Fc alpha receptor; Fc fragment of IgA, receptor for; CD_antigen: CD89]
products gene name :
[FcalphaR/CD89]
other gene names :
[FCAR; FCAR; CD89; FcalphaRI; CD89; IgA Fc receptor]
uniprot entry name :
FCAR_HUMAN
reactivity :
Human
sequence length :
191
specificity :
This kit recognizes natural and recombinant Human FcalphaR/CD89. No significant cross-reactivity or interference between Human FcalphaR/CD89 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.781-50ng/mL. Sensitivity: Min: 0.469ng/mL; Max: 50ng/mL
other info2 :
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human FcalphaR/CD89 concentrations in serum, plasma and other biological fluids.
products description :
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to FcalphaR/CD89. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for FcalphaR/CD89 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain FcalphaR/CD89, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of FcalphaR/CD89. You can calculate the concentration of FcalphaR/CD89 in the samples by comparing the OD of the samples to the standard curve.
ncbi gi num :
1439558
ncbi acc num :
AAC50595.1
uniprot acc num :
P24071
ncbi mol weight :
28,343 Da
ncbi pathways :
Phagosome Pathway (153910); Phagosome Pathway (153859); Staphylococcus Aureus Infection Pathway (172846); Staphylococcus Aureus Infection Pathway (171867)
ncbi summary :
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
FCAR: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. 11 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Immunoglobulin superfamily. Chromosomal Location of Human Ortholog: 19q13.42. Cellular Component: integral to plasma membrane; extracellular region; plasma membrane. Molecular Function: IgA binding. Biological Process: immune response
size1 :
24-Strip-Wells
price1 :
215 USD
size2 :
48-Strip-Wells
price2 :
410
size3 :
96-Strip-Wells
price3 :
490
size4 :
5x96-Strip-Wells
price4 :
2040
size5 :
10x96-Strip-Wells
price5 :
3590
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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