Human PRDX1 (Peroxiredoxin 1) ELISA Kit | MyBioSource MBS2502078 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human PRDX1 (Peroxiredoxin 1) ELISA Kit

catalog :

MBS2502078

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2502078

products type :

ELISA Kit

products full name :

Human PRDX1 (Peroxiredoxin 1) ELISA Kit

products short name :

[PRDX1]

other names :

[peroxiredoxin-1; Peroxiredoxin-1; peroxiredoxin-1; natural killer cell-enhancing factor A; natural killer-enhancing factor A; proliferation-associated gene A; proliferation-associated gene protein; thioredoxin peroxidase 2; thioredoxin-dependent peroxide reductase 2; peroxiredoxin 1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2]

products gene name :

[PRDX1]

other gene names :

[PRDX1; PRDX1; PAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A; PAGA; PAGB; TDPX2; NKEF-A; PAG]

uniprot entry name :

PRDX1_HUMAN

reactivity :

Human

sequence length :

199

specificity :

This kit recognizes natural and recombinantHumanPRDX1. No significant cross-reactivity or interference between HumanPRDX1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 15.625-1000pg/mL. Sensitivity: Min: 9.375pg/mL; Max: 1000pg/mL

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanPRDX1concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to PRDX1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PRDX1and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PRDX1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of PRDX1.You can calculate the concentration of PRDX1in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

32455266

ncbi acc num :

NP_859048.1

ncbi gb acc num :

NM_181697.2

uniprot acc num :

Q06830

ncbi mol weight :

22,110 Da

ncbi pathways :

Androgen Receptor Signaling Pathway (198806); Cellular Responses To Stress Pathway (645258); Coregulation Of Androgen Receptor Activity Pathway (138085); Detoxification Of Reactive Oxygen Species Pathway (1127552); Peroxisome Pathway (131226); Peroxisome Pathway (131126); Selenium Pathway (198825)

ncbi summary :

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]

uniprot summary :

PRDX1: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression. Protein type: Nuclear receptor co-regulator; EC 1.11.1.15; Oxidoreductase. Chromosomal Location of Human Ortholog: 1p34.1. Cellular Component: extracellular space; peroxisomal matrix; mitochondrial matrix; cytoplasm; melanosome; nucleolus; cytosol; nucleus. Molecular Function: protein binding; protein homodimerization activity; peroxidase activity; thioredoxin peroxidase activity; heme binding. Biological Process: cell proliferation; regulation of stress-activated MAPK cascade; retinal homeostasis; erythrocyte homeostasis; response to reactive oxygen species; removal of superoxide radicals; hydrogen peroxide catabolic process; natural killer cell mediated cytotoxicity; skeletal development; regulation of NF-kappaB import into nucleus

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590