catalog number :
MBS2501304
products type :
ELISA Kit
products full name :
Human FABP5 (Fatty Acid Binding Protein 5, Epidermal) ELISA Kit
products short name :
[FABP5]
other names :
[fatty acid-binding protein, epidermal; Fatty acid-binding protein, epidermal; fatty acid-binding protein, epidermal; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog; fatty acid binding protein 5 (psoriasis-associated); Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; PA-FABP]
products gene name :
[FABP5]
other gene names :
[FABP5; FABP5; EFABP; KFABP; E-FABP; PAFABP; PA-FABP; E-FABP; PA-FABP]
uniprot entry name :
FABP5_HUMAN
specificity :
This kit recognizes natural and recombinant Human FABP5. No significant cross-reactivity or interference between Human FABP5 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.313-20ng/mL. Sensitivity: Min: 0.188ng/mL; Max: 20ng/mL
products description :
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to FABP5. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for FABP5 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain FABP5, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of FABP5. You can calculate the concentration of FABP5 in the samples by comparing the OD of the samples to the standard curve.
ncbi acc num :
NP_001435.1
ncbi gb acc num :
NM_001444.2
ncbi mol weight :
15,164 Da
ncbi pathways :
PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Signal Transduction Pathway (477114); Signaling By Retinoic Acid Pathway (1127533)
ncbi summary :
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]
uniprot summary :
FABP5: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 8q21.13. Cellular Component: nucleoplasm; cytoplasm; cytosol. Molecular Function: protein binding; transporter activity; lipid binding; fatty acid binding. Biological Process: epidermis development; phosphatidylcholine biosynthetic process; glucose metabolic process; lipid metabolic process; glucose transport
size5 :
10x96-Strip-Wells