Human GCSFR (Colony Stimulating Factor Receptor, Granulocyte) ELISA Kit | MyBioSource MBS2500644 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human GCSFR (Colony Stimulating Factor Receptor, Granulocyte) ELISA Kit

catalog :

MBS2500644

quantity :

48-Strip-Wells

price :

410 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2500644

products type :

ELISA Kit

products full name :

Human GCSFR (Colony Stimulating Factor Receptor, Granulocyte) ELISA Kit

products short name :

GCSFR

other names :

granulocyte colony-stimulating factor receptor isoform d; Granulocyte colony-stimulating factor receptor; granulocyte colony-stimulating factor receptor; CD114 antigen; G-CSF receptor; G-CSF-R; colony stimulating factor 3 receptor (granulocyte); CD_antigen: CD114

products gene name :

GCSFR

other gene names :

CSF3R; CSF3R; CD114; GCSFR; GCSFR; G-CSF receptor; G-CSF-R

uniprot entry name :

CSF3R_HUMAN

reactivity :

Human

sequence length :

783

specificity :

This kit recognizes natural and recombinant Human GCSFR. No significant cross-reactivity or interference between Human GCSFR and analogues was observed.

storage stability :

Store at 4 degree C.

other info1 :

Samples: Serum, plasma and other biological fluids. Assay Type: Sandwich. Detection Range: 0.313-20ng/mL. Sensitivity: The minimum detectable dose of Human GCSFR is 0.188ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero).

other info2 :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human GCSFR concentrations in serum, plasma and other biological fluids.

products description :

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to GCSFR. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for GCSFR and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain GCSFR, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of GCSFR. You can calculate the concentration of GCSFR in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

27437045

ncbi acc num :

NP_758519.1

ncbi gb acc num :

NM_172313.2

uniprot acc num :

Q99062

ncbi mol weight :

86,609 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979); Pathways In Cancer (83105)

ncbi summary :

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]

uniprot summary :

GCSFR: the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variant isoforms have been described. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: 1p35-p34.3. Cellular Component: integral to plasma membrane; extracellular region. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity. Biological Process: neutrophil chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; signal transduction; cell adhesion. Disease: Neutrophilia, Hereditary

size1 :

48-Strip-Wells

price1 :

410 USD

size2 :

96-Strip-Wells

price2 :

490

more info or order :

MyBioSource product webpage