ELISA/assay

Human IGFALS(Insulin Like Growth Factor Binding Protein, Acid Labile Subunit)ELISA Kit

MBS2500615

48-Strip-Wells

410 USD

ELISA Kit

Human IGFALS(Insulin Like Growth Factor Binding Protein, Acid Labile Subunit)ELISA Kit

IGFALS

insulin-like growth factor-binding protein complex acid labile subunit isoform 2; Insulin-like growth factor-binding protein complex acid labile subunit; insulin-like growth factor-binding protein complex acid labile subunit; insulin-like growth factor binding protein complex acid labile chain; insulin-like growth factor binding protein, acid labile subunit

IGFALS

IGFALS; IGFALS; ALS; ACLSD; ALS; ALS

ALS_HUMAN

Human

605

This assay has high sensitivity and excellent specificity for detection of Human IGFALS. No significant cross-reactivity or interference between Human IGFALS and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human IGFALS and all the analogues, therefore, cross reaction may still exist.

Store at 4 degree C.

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 1.563--100ng/mL. Sensitivity: 0.938ng/mL

Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IGFALS in human serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IGFALS. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human IGFALS and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human IGFALS, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human IGFALS. You can calculate the concentration of Human IGFALS in the samples by comparing the OD of the samples to the standard curve.

4826772

NP_004961.1

NM_004970.2

P35858

70,236 Da

Metabolism Of Proteins Pathway (106230); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908)

The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

IGFALS: Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion. Protein type: Secreted; Secreted, signal peptide; Cell adhesion. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: nucleoplasm; extracellular space; extracellular region. Molecular Function: insulin-like growth factor binding. Biological Process: cellular protein metabolic process; cell adhesion; signal transduction. Disease: Acid-labile Subunit Deficiency

48-Strip-Wells

410 USD

96-Strip-Wells

490