Monkey LBP (Lipopolysaccharide Binding Protein) ELISA Kit | MyBioSource MBS2500029 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Monkey LBP (Lipopolysaccharide Binding Protein) ELISA Kit

catalog :

MBS2500029

quantity :

24-Strip-Wells

price :

235 USD

product information

catalog number :

MBS2500029

products type :

ELISA Kit

products full name :

Monkey LBP (Lipopolysaccharide Binding Protein) ELISA Kit

products short name :

[LBP]

other names :

[lipopolysaccharide-binding protein; Lipopolysaccharide-binding protein; lipopolysaccharide-binding protein; BPI fold containing family D, member 2; LPS-binding protein; lipopolysaccharide binding protein]

products gene name :

[LBP]

other gene names :

[LBP; LBP; BPIFD2; LBP]

uniprot entry name :

LBP_HUMAN

reactivity :

Monkey

sequence length :

481

specificity :

This kit recognizes Monkey IP-10/CXCL10 in samples. No significant cross-reactivity or interference between Monkey IP-10/CXCL10and analogues was observed.

storage stability :

Store at 4 degree C.

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 7.81-500pg/mL. Sensitivity: 4.69pg/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, midrange and high level Monkey IP-10/CXCL10were tested 20times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, midrange and high level Monkey IP-10/CXCL10were testedon 3 different plates, 20replicates in eachplate

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Monkey IP-10/CXCL10 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Monkey IP-10/CXCL10. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Monkey IP-10/CXCL10 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Monkey IP-10/CXCL10, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Monkey IP-10/CXCL10. You can calculate the concentration of Monkey IP-10/CXCL10 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

31652249

ncbi acc num :

NP_004130.2

ncbi gb acc num :

NM_004139.4

uniprot acc num :

P18428

ncbi mol weight :

53,384 Da

ncbi pathways :

IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Innate Immune System Pathway (106387); NF-kappa B Signaling Pathway (634527); Regulation Of Toll-like Receptor Signaling Pathway (920955); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149); Toll Like Receptor 4 (TLR4) Cascade Pathway (106398); Toll-Like Receptors Cascades Pathway (106388); Toll-like Receptor Signaling Pathway (83076)

ncbi summary :

The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]

uniprot summary :

LBP: Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 20q11.23. Cellular Component: extracellular space; cell surface; extracellular region. Molecular Function: protein binding; lipopolysaccharide binding; receptor binding. Biological Process: positive regulation of tumor necrosis factor biosynthetic process; detection of molecule of bacterial origin; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of interleukin-6 production; response to lipopolysaccharide; negative regulation of tumor necrosis factor production; defense response to Gram-negative bacterium; positive regulation of tumor necrosis factor production; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production; positive regulation of interleukin-8 production; lipopolysaccharide transport; defense response to Gram-positive bacterium; macrophage activation during immune response; toll-like receptor signaling pathway; acute-phase response; lipopolysaccharide-mediated signaling pathway; innate immune response; cellular defense response; opsonization; toll-like receptor 4 signaling pathway; positive regulation of macrophage activation

size1 :

24-Strip-Wells

price1 :

235 USD

size2 :

48-Strip-Wells

price2 :

450

size3 :

96-Strip-Wells

price3 :

535

size4 :

5x96-Strip-Wells

price4 :

2255

size5 :

10x96-Strip-Wells

price5 :

3975