product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal (IgG) to Human CSF2RB / CD131
catalog :
MBS247912
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS247912
products type :
Antibody
products full name :
Rabbit Polyclonal (IgG) to Human CSF2RB / CD131
products short name :
CSF2RB / CD131
products name syn :
Anti-CSF2RB / CD131 Antibody (aa559-608) IHC-plus; CSF2RB; CD131 antigen; CDw131; IL3RB; IL5RB; SMDP5; CD131; GM-CSF receptor beta chain; Human CSF2RB; CD131
other names :
cytokine receptor common subunit beta; Cytokine receptor common subunit beta; cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131
products gene name :
CSF2RB
products gene name syn :
CD131
other gene names :
CSF2RB; CSF2RB; CD131; IL3RB; IL5RB; SMDP5; CDw131; IL3RB; IL5RB
uniprot entry name :
IL3RB_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
897
specificity :
IL-3R beta antibody detects endogenous levels of total IL-3R beta protein.
purity :
Immunoaffinity Purified
form :
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
concentration :
1 mg/ml
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:1000), IHC-P (10 ug/ml), WB (1:500 - 1:1000)
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human IL-3R beta (aa559-608).
other info2 :
Immunogen: CSF2RB / CD131 antibody was raised against synthetic peptide from human IL-3R beta (aa559-608). Antigen Modification: aa559-608
products description :
CSF2RB is a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defective CSF2RB has been reported to be associated with protein alveolar proteinosis.
ncbi gi num :
4559408
ncbi acc num :
NP_000386.1
ncbi gb acc num :
NM_000395.2
uniprot acc num :
P32927
ncbi mol weight :
97,976 Da
ncbi pathways :
Apoptosis Pathway (83060); Apoptosis Pathway (470); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); G Beta:gamma Signalling Through PI3Kgamma Pathway (119540); G-protein Beta:gamma Signalling Pathway (119539); GPCR Downstream Signaling Pathway (119548); GPVI-mediated Activation Cascade Pathway (106036); Hemostasis Pathway (106028)
ncbi summary :
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
uniprot summary :
CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; interleukin-5 receptor activity; interleukin-3 receptor activity; receptor activity. Biological Process: response to lipopolysaccharide; respiratory gaseous exchange; signal transduction. Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5
size1 :
0.05 mg
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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