product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human Renal Dipeptidase / DPEP1
catalog :
MBS246856
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
product information
catalog number :
MBS246856
products type :
Antibody
products full name :
Rabbit Polyclonal to Human Renal Dipeptidase / DPEP1
products short name :
Renal Dipeptidase / DPEP1
products name syn :
Anti-Renal Dipeptidase / DPEP1 Antibody (N-Terminus) IHC-plus; DPEP1; Dipeptidase 1 (renal); Dehydropeptidase-I; Dipeptidase 1; HRDP; Microsomal dipeptidase; Renal dipeptidase; RDP; Human Renal Dipeptidase; DPEP1
other names :
dipeptidase 1; Dipeptidase 1; dipeptidase 1; hRDP; renal dipeptidase; dehydropeptidase-I; microsomal dipeptidase; dipeptidase 1 (renal); Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase; hRDP
products gene name :
DPEP1
other gene names :
DPEP1; DPEP1; MDP; RDP; MBD1; MDP; RDP; hRDP
uniprot entry name :
DPEP1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Gorilla, Human, Monkey
sequence length :
411
specificity :
Human DPEP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
1 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (10 ug/ml)
other info1 :
Target Species: Human. Immunogen Description: Synthetic 14 amino acid peptide from N-terminus of human DPEP1. Percent identity with other species by BLAST analysis: Human, Gorilla, Marmoset (100%); Monkey (86%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: Renal Dipeptidase / DPEP1 antibody was raised against synthetic 14 amino acid peptide from N-terminus of human DPEP1. Percent identity with other species by BLAST analysis: Human, Gorilla, Marmoset (100%); Monkey (86%). Antigen Modification: N-Terminus
products categories :
Family: Exopeptidase. Subfamily: Metallopeptidase M19
ncbi gi num :
4758190
ncbi acc num :
NP_004404.1
ncbi gb acc num :
NM_004413.3
uniprot acc num :
P16444
ncbi mol weight :
45,674 Da
ncbi pathways :
Aflatoxin Activation And Detoxification Pathway (1127511); Arachidonic Acid Metabolism Pathway (685553); Biological Oxidations Pathway (105698); Defective ACY1 Causes Encephalopathy Pathway (1127638); Disease Pathway (530764); Eicosanoid Synthesis Pathway (198888); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Synthesis Of Leukotrienes (LT) And Eoxins (EX) Pathway (730334)
ncbi summary :
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]
uniprot summary :
DPEP1: Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. Belongs to the peptidase M19 family. Protein type: EC 3.4.13.19; Protease; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 16q24.3. Cellular Component: extracellular space; microvillus membrane; apical part of cell; apical plasma membrane; plasma membrane; cell junction; nucleus. Molecular Function: protein binding; metalloexopeptidase activity; zinc ion binding; dipeptidyl-peptidase activity; caspase inhibitor activity. Biological Process: glutathione metabolic process; xenobiotic metabolic process; arachidonic acid metabolic process; leukotriene metabolic process; homocysteine metabolic process; negative regulation of caspase activity; proteolysis; negative regulation of cell migration; antibiotic metabolic process; negative regulation of apoptosis
size1 :
0.05 mg
price1 :
495 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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