product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal (IgG) to Human AFP / Alpha Fetoprotein
catalog :
MBS246829
quantity :
0.05 mL
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS246829
products type :
Antibody
products full name :
Rabbit Polyclonal (IgG) to Human AFP / Alpha Fetoprotein
products short name :
AFP / Alpha Fetoprotein
products name syn :
Anti-AFP / Alpha Fetoprotein Antibody (Internal) IHC-plus; Alpha-1-fetoprotein; Alpha-fetoprotein; HPAFP; Alpha-fetoglobulin; FETA; Human AFP; Alpha Fetoprotein
other names :
alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-fetoglobulin; alpha-1-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
products gene name :
AFP
other gene names :
AFP; AFP; AFPD; FETA; HPAFP; HPAFP
uniprot entry name :
FETA_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
609
purity :
Affinity Purified
form :
PBS, pH 7.4, 0.02% sodium azide
concentration :
1 mg/ml
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA, IHC-P (2.5 ug/ml), WB
other info1 :
Target Species: Human. Immunogen Description: A 15 amino acid peptide from the internal region of human AFP protein.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: AFP / Alpha Fetoprotein antibody was raised against a 15 amino acid peptide from the internal region of human AFP protein. Antigen Modification: Internal
ncbi gi num :
4501989
ncbi acc num :
NP_001125.1
ncbi gb acc num :
NM_001134.2
uniprot acc num :
P02771
ncbi mol weight :
68,678 Da
ncbi pathways :
Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
uniprot summary :
AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cytoplasm. Molecular Function: metal ion binding. Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of
size1 :
0.05 mL
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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