Mouse Monoclonal [clone 1H3] (IgG2a,k) to Human EIF2S3 / EIF2G | MyBioSource MBS246015 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse Monoclonal [clone 1H3] (IgG2a,k) to Human EIF2S3 / EIF2G

catalog :

MBS246015

quantity :

0.05 mg

price :

605 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[1H3]

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Anti-EIF2S3 / EIF2G antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

image 2 :

Detection limit for recombinant GST tagged EIF2S3 is 0.3 ng/ml as a capture antibody.

product information

catalog number :

MBS246015

products type :

Antibody

products full name :

Mouse Monoclonal [clone 1H3] (IgG2a,k) to Human EIF2S3 / EIF2G

products short name :

[EIF2S3 / EIF2G]

products name syn :

[Anti-EIF2S3 / EIF2G Antibody (clone 1H3) IHC-plus; EIF2S3; EIF-2-gamma X; EIF2; EIF2gamma; EIF-2gA; EIF-2gX; EIF2G; Human EIF2S3; EIF2G]

other names :

[eukaryotic translation initiation factor 2 subunit 3; Eukaryotic translation initiation factor 2 subunit 3; eukaryotic translation initiation factor 2 subunit 3; eIF-2gX; eIF-2-gamma X; eukaryotic translation initiation factor 2G; eukaryotic translation initiation factor 2 subunit gamma X; eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; Eukaryotic translation initiation factor 2 subunit gamma X; eIF-2-gamma X; eIF-2gX]

products gene name :

[EIF2S3]

products gene name syn :

[EIF2G]

other gene names :

[EIF2S3; EIF2S3; EIF2; EIF2G; eIF-2gA; EIF2gamma; EIF2G; eIF-2-gamma X; eIF-2gX]

uniprot entry name :

IF2G_HUMAN

clonality :

Monoclonal

isotype :

IgG2a,k

clone :

[1H3]

host :

Mouse

reactivity :

Human

sequence length :

472

specificity :

Human EIF2S3 / EIF2G

purity :

Protein A Purified

form :

PBS, pH 7.4. Sourced in Ascites.

concentration :

0.5 mg/ml

storage stability :

Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

tested application :

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

app notes :

ELISA, IHC-P (5 ug/ml), WB. Usage: Sandwich ELISA: Recombinant protein. Western Blot: Recombinant protein.

image1 heading :

Immunohistochemistry (IHC)

image2 heading :

ELISA (EIA)

other info1 :

Target Species: Human. Immunogen Description: Recombinant protein. Immunogen Species: EIF2S3/EIF2G antibody was raised against Human.

other info2 :

Immunogen Type: Recombinant protein

ncbi gi num :

4503507

ncbi acc num :

NP_001406.1

ncbi gb acc num :

NM_001415.3

uniprot acc num :

P41091

ncbi mol weight :

51,109 Da

ncbi pathways :

Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway (105970); Cap-dependent Translation Initiation Pathway (105967); Eukaryotic Translation Initiation Pathway (105966); Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway (105969); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (105973); Gene Expression Pathway (105937); L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway (160955); Metabolism Of Proteins Pathway (106230); RNA Transport Pathway (177876); RNA Transport Pathway (175229)

ncbi summary :

The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]

uniprot summary :

eIF2-gamma: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. Protein type: Translation initiation; Translation. Chromosomal Location of Human Ortholog: Xp22.2-p22.1. Cellular Component: cytoplasm; nucleus; cytosol. Molecular Function: GTPase activity; protein binding; GTP binding; translation factor activity, nucleic acid binding; translation initiation factor activity. Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression

size1 :

0.05 mg

price1 :

605 USD

more info or order :

MyBioSource product webpage