product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Monoclonal [clone GFA-02] (IgG1) to Pig GFAP
catalog :
MBS245874
quantity :
0.05 mg
price :
495 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GFA-02
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS245874
products type :
Antibody
products full name :
Mouse Monoclonal [clone GFA-02] (IgG1) to Pig GFAP
products short name :
GFAP
products name syn :
Anti-GFAP Antibody (clone GFA-02) IHC-plus; GFAP; Pig GFAP
other names :
glial fibrillary acidic protein isoform 1; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein
products gene name :
GFAP
other gene names :
GFAP; GFAP; GFAP
uniprot entry name :
GFAP_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
GFA-02
host :
Mouse
reactivity :
Human, Pig
sequence length :
432
specificity :
GFA-02 reacts with Glial Fibrillary Acid Protein (52 kD). GFAP is the major protein of glial filaments in astrocytes and ependymal cells. In the peripheral nervous system GFAP is found in Schwann cells.
purity :
Purified
form :
PBS, 0.05% sodium azide
concentration :
0.1mg/ml
storage stability :
Store at 4 degree C.
tested application :
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
app notes :
Flo, IHC-Fr, IHC-P (1:100), IP, WB. Usage: Can be used for identifying astrocytomas and ependymomas.
other info1 :
Target Species: Pig. Immunogen Description: Crude preparation from porcine spinal cord. Usage Summary: Can be used for identifying astocytomas and ependymomas.
other info2 :
Immunogen: GFAP antibody was raised against crude preparation from porcine spinal cord. Summary: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the developmental of the central nervous system, distinguishes astrocytes from other glial cells.
products description :
Glial fibrillary acidic protein is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage. It is used frequently as an astrocyte marker.
ncbi gi num :
4503979
ncbi acc num :
NP_002046.1
ncbi gb acc num :
NM_002055.4
uniprot acc num :
P14136
ncbi mol weight :
49,508 Da
ncbi pathways :
Neural Crest Differentiation Pathway (672460); Nuclear Signaling By ERBB4 Pathway (530744); Signal Transduction Pathway (477114); Signaling By ERBB4 Pathway (530741); Spinal Cord Injury Pathway (739007)
ncbi summary :
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
uniprot summary :
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: membrane; cytoplasm; intermediate filament; cytosol. Molecular Function: integrin binding; structural constituent of cytoskeleton; kinase binding. Biological Process: Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; regulation of neurotransmitter uptake; response to wounding; intermediate filament organization; neurite regeneration; astrocyte development. Disease: Alexander Disease
size1 :
0.05 mg
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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