catalog number :
MBS245614
products full name :
Mouse Monoclonal [clone IT-Ks 20.10] (IgG1) to Human KRT20 / CK20 / Cytokeratin 20
products short name :
KRT20 / CK20 / Cytokeratin 20
products name syn :
Anti-KRT20 / CK20 / Cytokeratin 20 Antibody (clone IT-Ks 20.10, FITC) IHC-plus; KRT20; Cytokeratin-20; Cytokeratin 20; CK20; K20; Keratin 20; Keratin-20; KRT21; CK-20; Protein IT; Human KRT20; CK20; Cytokeratin 20
other names :
keratin, type I cytoskeletal 20; Keratin, type I cytoskeletal 20; keratin, type I cytoskeletal 20; keratin-20; protein IT; cytokeratin 20; cytokeratin-20; keratin 20; Cytokeratin-20; CK-20; Keratin-20; K20; Protein IT
products gene name :
KRT20
other gene names :
KRT20; KRT20; K20; CD20; CK20; CK-20; KRT21; CK-20; K20
uniprot entry name :
K1C20_HUMAN
reactivity :
Human, Pig, Rat
specificity :
Human, pig, and rat. Polypeptide reacting: Protein IT Reactivities on cultured Cell lines that have been tested so far are HT-29, LoVo, DLD-1, SW 1116 CaCo-2, RT-4
purity :
Affinity Purified
form :
Supplied as a liquid. No preservatives added.
concentration :
0.2 mg/ml
storage stability :
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS)
app notes :
IHC-P (1:50), FC-Optimal dilution to be determined by the researcher)
other info1 :
Target: KRT20/ CK20/ Cytokeratin 20. Family/Subfamily: Keratin/not assigned-Keratin. Target Species: Human. Immunogen Species: KRT20/CK20/CYtokeratin 20 antibody was raised against Human.
other info2 :
Antibody Modification: FITC
products categories :
Family: Keratin
ncbi acc num :
NP_061883.1
ncbi gb acc num :
NM_019010.2
ncbi mol weight :
48,487 Da
ncbi summary :
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
uniprot summary :
K20: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: cytoplasm; intermediate filament. Molecular Function: protein binding; structural constituent of cytoskeleton. Biological Process: regulation of protein secretion; apoptosis; cellular response to stress; intermediate filament organization