catalog number :
MBS245506
products full name :
Hamster Monoclonal [clone LG.3A10] (IgG1) to Mouse CD27
products short name :
CD27
products name syn :
Anti-CD27 Antibody (clone LG.3A10, FITC) IHC-plus; CD27; CD27 antigen; CD27 molecule; S152; T14; T-cell activation antigen CD27; CD27L receptor; T cell activation antigen S152; TNFRSF7; Tp55; Mouse CD27
other names :
CD27 antigen; CD27 antigen; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; CD27 molecule; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD_antigen: CD27
products gene name :
CD27
other gene names :
CD27; CD27; T14; S152; Tp55; TNFRSF7; S152. LPFS2; TNFRSF7
uniprot entry name :
CD27_HUMAN
reactivity :
Human, Mouse
specificity :
Anti-mouse CD27 Monoclonal Antibody is specific for the mouse CD27 receptor.
purity :
Protein G Purified
form :
PBS, 0.02% sodium azide, EIA grade BSA.
concentration :
0.1 mg/ml
storage stability :
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Flow Cytometry (FC/FACS)
app notes :
Flo (0.5 ug/10E6 cells), IHC-Fr, IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Mouse. Immunogen Description: MCD27 tag expressing clones AR0524 and AR0530.
other info2 :
Immunogen: CD27 antibody was raised against mCD27 tag expressing clones AR0524 and AR0530. Antibody Modification: FITC
products categories :
Family: TNF Receptor
ncbi acc num :
NP_001233.1
ncbi gb acc num :
NM_001242.4
ncbi mol weight :
29,137 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]