product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Monoclonal [clone VG-1] (IgG1) to Human VEGFA / VEGF
catalog :
MBS245485
quantity :
0.05 mg
price :
495 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VG-1
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS245485
products type :
Antibody
products full name :
Mouse Monoclonal [clone VG-1] (IgG1) to Human VEGFA / VEGF
products short name :
VEGFA / VEGF
products name syn :
Anti-VEGFA / VEGF Antibody (clone VG-1) IHC-plus; VEGFA; VPF; Vascular permeability factor; VEGF; VEGF-A; MVCD1; Human VEGFA; VEGF
other names :
vascular endothelial growth factor A isoform b; Vascular endothelial growth factor A; vascular endothelial growth factor A; vascular permeability factor; vascular endothelial growth factor A; Vascular permeability factor; VPF
products gene name :
VEGFA
products gene name syn :
VEGF
other gene names :
VEGFA; VEGFA; VPF; VEGF; MVCD1; VEGF; VEGF-A; VPF
uniprot entry name :
VEGFA_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
VG-1
host :
Mouse
reactivity :
Human
sequence length :
395
specificity :
the 121, 165, and 189 VEGF isoforms of Human origin
purity :
Protein A/G Purified
form :
PBS, 0.1% sodium azide, 0.2% gelatin. Sourced in TCS.
concentration :
0.1 mg/ml
storage stability :
Store at +4 degree C. DO NOT FREEZE.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA, IHC-P (1:50), WB (1:200). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Recombinant VEGF.
other info2 :
Immunogen Type: Recombinant protein. Immunogen: VEGFA / VEGF antibody was raised against recombinant VEGF.
products categories :
Family: PDGF
products description :
VEGFA was originally isolated as a heparin-binding secreted factor from bovine pituitary folliculo-stellate cells. It is a direct acting mitogen specific for vascular endothelial cells and capable of stimulating angiogenesis in vivo. In addition to inducing endothelial cell proliferation it promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Molecular cloning has revealed multiple forms of VEGFA arising from alternative splicing of the RNA transcript.
ncbi gi num :
76781481
ncbi acc num :
NP_003367.4
ncbi gb acc num :
NM_003376.5
uniprot acc num :
P15692
ncbi mol weight :
34,406 Da
ncbi pathways :
Angiogenesis Pathway (198772); Axon Guidance Pathway (105688); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Cellular Response To Hypoxia Pathway (645259); Cellular Responses To Stress Pathway (645258); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Developmental Biology Pathway (477129); EPH-Ephrin Signaling Pathway (1127691)
ncbi summary :
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]
size1 :
0.05 mg
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

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