catalog number :
MBS245458
products full name :
Mouse Monoclonal (IgG1) to Human CD34
products short name :
CD34
products name syn :
Anti-CD34 Antibody (FITC) IHC-plus; CD34; CD34 molecule; CD34 antigen; Human CD34
other names :
hematopoietic progenitor cell antigen CD34 isoform b; Hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell antigen CD34; CD34 antigen; CD34 molecule; CD_antigen: CD34
products gene name :
CD34
other gene names :
CD34; CD34
uniprot entry name :
CD34_HUMAN
specificity :
Recognizes human CD34 Class III epitope which is resistant to neuraminidase, chymopapain and glycoprotease.
form :
PBS, 0.1% sodium azide and a stabilizing agent.
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Flow Cytometry (FC/FACS)
app notes :
Flo, IHC-Fr, IHC-P (1:50). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: CD34.
other info2 :
Immunogen: CD34 antibody was raised against cD34. Antibody Modification: FITC
products description :
CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells. CD34 is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes.
ncbi acc num :
NP_001764.1
ncbi gb acc num :
NM_001773.2
ncbi mol weight :
35,011 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!C-MYB Transcription Factor Network Pathway 138073!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413
ncbi summary :
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]