catalog number :
MBS245435
products full name :
Mouse Monoclonal [clone J3H10] (IgG2b,k) to Human YWHAG / 14-3-3 Gamma
products short name :
YWHAG / 14-3-3 Gamma
products name syn :
Anti-YWHAG / 14-3-3 Gamma Antibody (aa1-247, clone J3H10) IHC-plus; YWHAG; 14-3-3GAMMA; 14-3-3 gamma; 14-3-3 protein gamma; KCIP-1; Human YWHAG; 14-3-3 Gamma
other names :
14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 protein gamma; KCIP-1; 14-3-3 gamma; protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma; Protein kinase C inhibitor protein 1; KCIP-1
products gene name :
YWHAG
other gene names :
YWHAG; YWHAG; PPP1R170; 14-3-3GAMMA; KCIP-1
uniprot entry name :
1433G_HUMAN
purity :
Protein G Purified
form :
PBS, pH 7.4, 0.1% sodium azide. Sourced in Ascites.
storage stability :
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA, IHC-P (5 ug/ml), WB (1:1000 - 1:2000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Recombinant human 14-3-3 gamma (1-247aa) purified from E Coli. NCBI Accession No.: NP_036611.
other info2 :
Immunogen Type: Recombinant protein. Immunogen: YWHAG / 14-3-3 Gamma antibody was raised against recombinant human 14-3-3 gamma (1-247aa) purified from E Coli. NCBI Accession No.: NP_036611. Antigen Modification: aa1-247
ncbi acc num :
NP_036611.2
ncbi gb acc num :
NM_012479.3
ncbi mol weight :
28,303 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Anchoring Of The Basal Body To The Plasma Membrane Pathway 1127503!!Apoptosis Pathway 105648!!Assembly Of The Primary Cilium Pathway 1127502!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]