product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Monoclonal [clone 2B6] (IgG2b,k) to Human NT5E / eNT / CD73
catalog :
MBS245390
quantity :
0.05 mg
price :
495 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B6
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS245390
products type :
Antibody
products full name :
Mouse Monoclonal [clone 2B6] (IgG2b,k) to Human NT5E / eNT / CD73
products short name :
NT5E / eNT / CD73
products name syn :
Anti-NT5E / eNT / CD73 Antibody (aa27-252, clone 2B6) IHC-plus; NT5E; 5-nucleotidase; ecto (CD73); 5'-nucleotidase; 5 nucleotidase (CD73); 5-NT; 5-nucleotidase; 5'-nucleotidase; ecto (CD73); CD73; CD73 antigen; E5NT; Ecto-5-nucleotidase; ENT; EN; NT; Purine 5-Prime-Nucleotidase; NT5; NTE; Human NT5E; eNT; CD73
other names :
5'-nucleotidase isoform 1 preproprotein; 5'-nucleotidase; 5'-nucleotidase; 5'-NT; ecto-5'-nucleotidase; Purine 5-Prime-Nucleotidase; 5'-nucleotidase, ecto (CD73); Ecto-5'-nucleotidase; CD_antigen: CD73
products gene name :
NT5E
products gene name syn :
eNT; CD73
other gene names :
NT5E; NT5E; NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA; NT5; NTE; 5'-NT
uniprot entry name :
5NTD_HUMAN
clonality :
Monoclonal
isotype :
IgG2b,k
clone :
2B6
host :
Mouse
reactivity :
Human
sequence length :
574
purity :
Protein G Purified
form :
PBS, pH 7.4, 0.1% sodium azide
concentration :
1 mg/ml
storage stability :
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA, IHC-P (10 ug/ml), WB (1:1000 - 1:2000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Recombinant human CD73 (27-252aa) purified from E Coli.
other info2 :
Immunogen Type: Recombinant protein. Immunogen: NT5E / eNT / CD73 antibody was raised against recombinant human CD73 (27-252aa) purified from E Coli. Antigen Modification: aa27-252
ncbi gi num :
4505467
ncbi acc num :
NP_002517.1
ncbi gb acc num :
NM_002526.3
uniprot acc num :
P21589
ncbi mol weight :
57,949 Da
ncbi summary :
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
uniprot summary :
NT5E: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Homodimer; disulfide-linked. Belongs to the 5 -nucleotidase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Nucleotide Metabolism - purine; Membrane protein, GPI anchor; Phosphatase (non-protein); EC 3.1.3.5; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Membrane protein, integral; Nucleotide Metabolism - pyrimidine. Chromosomal Location of Human Ortholog: 6q14-q21. Cellular Component: cell surface; membrane; cytoplasm; plasma membrane. Molecular Function: 5 -nucleotidase activity; metal ion binding; nucleotide binding. Biological Process: pyrimidine nucleoside catabolic process; pyrimidine base metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; adenosine biosynthetic process; negative regulation of inflammatory response; purine nucleotide catabolic process; DNA metabolic process; purine base metabolic process; AMP catabolic process. Disease: Calcification Of Joints And Arteries
size1 :
0.05 mg
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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