catalog number :
MBS245308
products full name :
Rabbit Polyclonal to Human S100A1 / S100
products short name :
S100A1 / S100
products name syn :
Anti-S100A1 / S100 Antibody (C-Terminus) IHC-plus; S100A1; S100 alpha; S100-alpha; Protein S100-A1; S-100 protein alpha chain; S100; S-100 protein subunit alpha; S100A; Human S100A1; S100
other names :
protein S100-A1; Protein S100-A1; protein S100-A1; S100 alpha; S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1; S100 protein, alpha polypeptide; S100 calcium binding protein A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1
products gene name :
S100A1
products gene name syn :
S100
other gene names :
S100A1; S100A1; S100; S100A; S100-alpha; S100A
uniprot entry name :
S10A1_HUMAN
form :
20 mM Tris-HCl, pH 8.0, 20 mg/ml BSA, 0.05% sodium azide
storage stability :
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Peptide derived from C-terminal sequence of human S100-A1 protein.
other info2 :
Immunogen: S100A1 / S100 antibody was raised against peptide derived from C-terminal sequence of human S100-A1 protein. Antigen Modification: C-Terminus
products categories :
Family: S-100
products description :
S100A1 has been suggested to be a regulator of myocardial contractility. S100A1 improves cardiac contractile performance both by regulating sarcoplasmic reticulum calcium ion handling and myofibrillar calcium ion responsiveness. S100 is an astrocyte marker.
ncbi acc num :
NP_006262.1
ncbi gb acc num :
NM_006271.1
ncbi mol weight :
10,546 Da
ncbi summary :
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]