This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Mouse Monoclonal [clone 2F7B2] (IgG1) to Human PECAM-1 / CD31
catalog :
MBS245247
quantity :
0.05 mg
price :
495 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2F7B2
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS245247
products type :
Antibody
products full name :
Mouse Monoclonal [clone 2F7B2] (IgG1) to Human PECAM-1 / CD31
products short name :
PECAM-1 / CD31
products name syn :
Anti-PECAM-1 / CD31 Antibody (clone 2F7B2) IHC-plus; PECAM1; CD31; CD31 antigen; EndoCAM; PECA1; PECAM-1; GPIIA; Human PECAM-1; CD31
other names :
platelet endothelial cell adhesion molecule; Platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule; CD31 antigen; platelet/endothelial cell adhesion molecule 1; EndoCAM; GPIIA'; PECA1; CD_antigen: CD31
products gene name :
PECAM-1
products gene name syn :
CD31
other gene names :
PECAM1; PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM; PECAM-1
uniprot entry name :
PECA1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2F7B2
host :
Mouse
reactivity :
Human
sequence length :
738
specificity :
Ni-NTA purified recombinant CD31 expressed in E Coli strain BL21 (DE3).
purity :
Affinity Purified
form :
PBS, pH 7.2, 0.02% sodium azide.
concentration :
0.5 mg/ml
storage stability :
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:10000), IHC-P (5 ug/ml), WB (1:500 - 1:2000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Recombinant human PECAM1 / CD31.
other info2 :
Immunogen Type: Recombinant protein. Immunogen: PECAM-1 / CD31 antibody was raised against recombinant human PECAM1 / CD31.
products description :
CD31 (PECAM1) is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31 is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
ncbi gi num :
110347451
ncbi acc num :
NP_000433.3
ncbi gb acc num :
NM_000442.3
uniprot acc num :
P16284
ncbi mol weight :
81,378 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (106062); Extracellular Matrix Organization Pathway (576262); Hemostasis Pathway (106028); Integrin Cell Surface Interactions Pathway (106110); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Malaria Pathway (152665); Malaria Pathway (152657)
ncbi summary :
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
uniprot summary :
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 17q23.3. Cellular Component: extracellular space; platelet alpha granule membrane; integral to membrane; plasma membrane; cell junction. Molecular Function: protein binding. Biological Process: platelet activation; extracellular matrix organization and biogenesis; platelet degranulation; diapedesis; cell recognition; blood coagulation; signal transduction; cell adhesion; leukocyte migration; phagocytosis
size1 :
0.05 mg
price1 :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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