Mouse Monoclonal [clone 2D3] (IgG2b,k) to Human ICOSLG / ICOSL / ICOS Ligand | MyBioSource MBS245174 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse Monoclonal [clone 2D3] (IgG2b,k) to Human ICOSLG / ICOSL / ICOS Ligand

catalog :

MBS245174

quantity :

0.05 mg

price :

495 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D3

reactivity :

human

application :

immunohistochemistry, flow cytometry, FACS

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS245174

products type :

Antibody

products full name :

Mouse Monoclonal [clone 2D3] (IgG2b,k) to Human ICOSLG / ICOSL / ICOS Ligand

products short name :

ICOSLG / ICOSL / ICOS Ligand

products name syn :

Anti-ICOSLG / ICOSL / ICOS Ligand Antibody (clone 2D3) IHC-plus; ICOSLG; B7RP1; B7 homolog 2; B7 homologue 2; B7-H2; B7H2; B7RP-1; CD275 antigen; ICOS ligand; GL50; ICOS-L; ICOSL; KIAA0653; B7-like protein Gl50; B7-related protein 1; CD275; LICOS; Human ICOSLG; ICOSL; ICOS Ligand

other names :

ICOS ligand isoform b; ICOS ligand; ICOS ligand; B7 homolog 2; B7 homologue 2; B7-like protein Gl50; B7-related protein 1; transmembrane protein B7-H2 ICOS ligand; inducible T-cell co-stimulator ligand; B7 homolog 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD_antigen: CD275

products gene name :

ICOSLG

other gene names :

ICOSLG; ICOSLG; B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; B7H2; B7RP1; ICOSL; KIAA0653; B7-H2; B7RP-1

uniprot entry name :

ICOSL_HUMAN

clonality :

Monoclonal

isotype :

IgG2b,k

clone :

2D3

host :

Mouse

reactivity :

Human

sequence length :

309

specificity :

Human ICOSL/CD275/B7H2

purity :

Affinity Purified

form :

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.

concentration :

0.5 mg/ml

storage stability :

+4 degree C. Store undiluted.

tested application :

Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS)

app notes :

Flo (0.5 ug/10E6 cells), IHC-P (1:50). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target Species: Human. Immunogen Description: Recombinant full-length human ICOSLG / ICOSL. Human B7H2-mIg fusion protein.

other info2 :

Immunogen Type: Recombinant protein. Immunogen: ICOSLG / ICOSL / ICOS Ligand antibody was raised against recombinant full-length human ICOSLG / ICOSL. Human B7H2-mIg fusion protein.

ncbi gi num :

545688560

ncbi acc num :

NP_001269979.1

ncbi gb acc num :

NM_001283050.1

uniprot acc num :

O75144

ncbi mol weight :

20,120 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Costimulation By The CD28 Family Pathway (119552); Immune System Pathway (106386); Intestinal Immune Network For IgA Production Pathway (128760); Intestinal Immune Network For IgA Production Pathway (128670)

uniprot summary :

ICOSLG: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function. Belongs to the immunoglobulin superfamily. BTN/MOG family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: integral to membrane; plasma membrane. Molecular Function: receptor binding. Biological Process: hyperosmotic response; T cell activation; B cell activation; T cell costimulation; defense response; positive regulation of activated T cell proliferation; signal transduction

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage

company information

MyBioSource

P.O. Box 153308
San Diego, CA 92195-3308

sales@mybiosource.com

https://www.mybiosource.com

1-888-627-0165

headquarters: USA

MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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