product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Monoclonal [clone OX-21] (IgG1) to Human CFI / Complement Factor I
catalog :
MBS245037
quantity :
0.05 mg
price :
495 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OX-21
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, FACS, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS245037
products type :
Antibody
products full name :
Mouse Monoclonal [clone OX-21] (IgG1) to Human CFI / Complement Factor I
products short name :
CFI / Complement Factor I
products name syn :
Anti-CFI / Complement Factor I Antibody (clone OX-21) IHC-plus; CFI; AHUS3; C3BINA; C3b-inactivator; C3B/C4B inactivator; Complement component I; Complement component factor i; Factor I; FI; KAF; I factor; I factor (complement); C3b-INA; Complement factor I; Light chain of factor I; Human CFI; Complement Factor I
other names :
complement factor I preproprotein; Complement factor I; complement factor I; C3b-inactivator; C3B/C4B inactivator; complement component I; light chain of factor I; Konglutinogen-activating factor; complement factor I heavy chain; complement control protein factor I; complement factor I; C3B/C4B inactivatorCleaved into the following 2 chains:Complement factor I heavy chain; Complement factor I light chain
products gene name :
CFI
other gene names :
CFI; CFI; FI; IF; KAF; AHUS3; ARMD13; C3BINA; C3b-INA; IF
uniprot entry name :
CFAI_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
OX-21
host :
Mouse
reactivity :
Human
sequence length :
583
specificity :
Purified human Complement Factor 1
purity :
Protein G Purified
form :
PBS, 0.02% sodium azide. Sourced in Ascites.
concentration :
1 mg/ml
storage stability :
Store at 4 degree C for short term applications. For long term storage, aliquot and store at -20 degree C.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), ELISA (EIA)
app notes :
ELISA, Flo, IHC-P (20 ug/ml), IP, WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Human complement factor I
other info2 :
Immunogen Type: Purified protein
products categories :
Family: Protease. Subfamily: Serine S1
ncbi gi num :
119392081
ncbi acc num :
NP_000195.2
ncbi gb acc num :
NM_000204.3
uniprot acc num :
P05156
ncbi mol weight :
65,750 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway 83073!!Complement And Coagulation Cascades Pathway 484!!Complement Cascade Pathway 106405!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Regulation Of Complement Cascade Pathway 576254!!Staphylococcus Aureus Infection Pathway 172846!!Staphylococcus Aureus Infection Pathway 171867
ncbi summary :
This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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