This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Mouse Monoclonal (IgG1) to Human ER Alpha / Estrogen Receptor
catalog :
MBS245027
quantity :
0.05 ml
price :
495 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
catalog number :
MBS245027
products type :
Antibody
products full name :
Mouse Monoclonal (IgG1) to Human ER Alpha / Estrogen Receptor
products short name :
ER Alpha / Estrogen Receptor
products name syn :
Anti-ER Alpha / Estrogen Receptor Antibody (aa410-592) IHC-plus; Era; ERalpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha; ER Alpha; Human ER Alpha; Estrogen Receptor
other names :
estrogen receptor isoform 1; Estrogen receptor; estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; nuclear receptor subfamily 3 group A member 1; estrogen receptor 1; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
products gene name :
ESR1
other gene names :
ESR1; ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1; ESR; NR3A1; ER
uniprot entry name :
ESR1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
host :
Mouse
reactivity :
Human
sequence length :
595
specificity :
Ni-NTA purified recombinant human ER-alpha (410-592aa) expressed in E Coli strain BL21 (DE3)
purity :
Protein A Purified
form :
PBS, pH 7.4, 0.03% sodium azide.
concentration :
1 mg/ml
storage stability :
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (1:800), WB (1:500 - 1:2000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Recombinant human ESR1 / Estrogen receptor.
other info2 :
Immunogen Type: Recombinant protein. Immunogen: ER Alpha / Estrogen Receptor antibody was raised against recombinant human ESR1 / Estrogen receptor. Antigen Modification: aa410-592
products categories :
Family: NHR. Subfamily: NR3 Steroid receptor
products description :
Estrogen receptor alpha, a NR3 Steroid Receptor, activates transcription of a wide variety of genes in response to estrogen, particularly in reproductive tissues. Recent studies have shown that ER alpha also can function in a ligand-independent and DNA binding- independent manner, as well as through cell-surface signaling. ER alpha functions have also been demonstrated via the selective ER modulator (SERM) ligands and their various ER signaling pathways.
ncbi gi num :
62821794
ncbi acc num :
NP_000116.2
ncbi gb acc num :
NM_000125.3
uniprot acc num :
P03372
ncbi mol weight :
35,547 Da
ncbi summary :
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
size :
0.05 ml
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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