product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Monoclonal [clone 68C1039.2] (IgG1) to Human IL25 / IL17E
catalog :
MBS245013
quantity :
0.05 mg
price :
495 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
68C1039.2
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS245013
products type :
Antibody
products full name :
Mouse Monoclonal [clone 68C1039.2] (IgG1) to Human IL25 / IL17E
products short name :
IL25 / IL17E
products name syn :
Anti-IL25 / IL17E Antibody (aa115-132, clone 68C1039.2) IHC-plus; IL25; Interleukin 17E; Interleukin 25; Interleukin-25; IL17E; IL-17E; IL-25; Interleukin-17E; Human IL25; IL17E
other names :
interleukin-25 isoform 1; Interleukin-25; interleukin-25; interleukin-17E; interleukin 25; Interleukin-17E; IL-17E
products gene name :
IL25
products gene name syn :
IL17E
other gene names :
IL25; IL25; IL17E; IL17E; IL-25; IL-17E
uniprot entry name :
IL25_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
68C1039.2
host :
Mouse
reactivity :
Human, Mouse
sequence length :
177
specificity :
A synthetic peptide of amino acids 115-132, obtained from the human IL-17E protein sequence, was used as immunogen
purity :
Protein G Purified
form :
PBS containing 0.05% BSA and 0.05% sodium azide. Sourced in TCS.
concentration :
0.5 mg/ml
storage stability :
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB (2 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human IL25 / IL-25.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: IL25 / IL17E antibody was raised against synthetic peptide from human IL25 / IL-25. Antigen Modification: aa115-132
products categories :
Family: Interleukin
products description :
The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8.
ncbi gi num :
12232485
ncbi acc num :
NP_073626.1
ncbi gb acc num :
NM_022789.3
uniprot acc num :
Q9H293
ncbi mol weight :
18,523 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL17 Signaling Pathway (920968)
ncbi summary :
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
uniprot summary :
IL25: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. Belongs to the IL-17 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide; Cytokine. Chromosomal Location of Human Ortholog: 14q11.2. Cellular Component: extracellular space. Molecular Function: cytokine activity; interleukin-17E receptor binding. Biological Process: response to fungus; inflammatory response to antigenic stimulus; response to nematode; eosinophil differentiation; positive regulation of transcription from RNA polymerase II promoter
size1 :
0.05 mg
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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