Rabbit Polyclonal to Human SLC5A1 / SGLT1 | MyBioSource MBS244887 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human SLC5A1 / SGLT1

catalog :

MBS244887

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS244887

products type :

Antibody

products full name :

Rabbit Polyclonal to Human SLC5A1 / SGLT1

products short name :

SLC5A1 / SGLT1

products name syn :

Anti-SLC5A1 / SGLT1 Antibody (Internal) IHC-plus; SLC5A1; D22S675; HSGLT1; Na(+)/glucose cotransporter 1; Na+/glucose cotransporter 1; SGLT1; NAGT; Sodium-glucose transporter 1; Sodium/glucose cotransporter 1; Human SLC5A1; SGLT1

other names :

sodium/glucose cotransporter 1 isoform 1; Sodium/glucose cotransporter 1; sodium/glucose cotransporter 1; Na+/glucose cotransporter 1; high affinity sodium-glucose cotransporter; solute carrier family 5 (sodium/glucose cotransporter), member 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1

products gene name :

SLC5A1

products gene name syn :

SGLT1

other gene names :

SLC5A1; SLC5A1; NAGT; SGLT1; D22S675; NAGT; SGLT1; Na(+)/glucose cotransporter 1

uniprot entry name :

SC5A1_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human

sequence length :

664

specificity :

Human SLC5A1 / SGLT1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

purity :

Immunoaffinity Purified

form :

PBS, less than 0.1% sodium azide.

concentration :

1 mg/ml

storage stability :

Upon arrival: Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze/thaw cycles.

tested application :

Immunohistochemistry (IHC - Paraffin)

app notes :

IHC-P (10 - 15 ug/ml)

other info1 :

Target Species: Human. Immunogen Description: Synthetic 14 amino acid peptide from internal region of human SLC5A1 / SGLT1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%); Monkey (86%).

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: SLC5A1 / SGLT1 antibody was raised against synthetic 14 amino acid peptide from internal region of human SLC5A1 / SGLT1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%); Monkey (86%). Epitope: Internal. Family/Subfamily: Transporter/solute: sodium symporter.

products categories :

Family: Transporter. Subfamily: Solute:sodium symporter

products description :

Actively transports glucose into cells by Na+ cotransport with a Na+ to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.

ncbi gi num :

4507031

ncbi acc num :

NP_000334.1

ncbi gb acc num :

NM_000343.3

uniprot acc num :

P13866

ncbi mol weight :

60,097 Da

ncbi pathways :

Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Carbohydrate Digestion And Absorption Pathway (170720); Carbohydrate Digestion And Absorption Pathway (170654); Disease Pathway (530764); Glycogen Storage Diseases Pathway (1127581); Hexose Transport Pathway (106198); Inositol Transporters Pathway (119575); Metabolism Pathway (477135); Metabolism Of Carbohydrates Pathway (106196)

ncbi summary :

This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

uniprot summary :

SLC5A1: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. Expressed mainly in intestine and kidney. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family. Chromosomal Location of Human Ortholog: 22q12.3. Cellular Component: brush border membrane; integral to plasma membrane; apical plasma membrane; plasma membrane; intercellular junction. Molecular Function: protein binding; glucose:sodium symporter activity. Biological Process: hexose transport; sodium ion transport; carbohydrate metabolic process; pathogenesis; glucose transport; transmembrane transport; metanephros development; intestinal absorption. Disease: Glucose/galactose Malabsorption

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage