catalog number :
MBS243487
products full name :
Rabbit Polyclonal to Human GPR139
products short name :
GPR139
products name syn :
Anti-GPR139 Antibody (Transmembrane Domain) IHC-plus; GPR139; G protein-coupled receptor 139; PGR3; GPRg1; Human GPR139
other names :
probable G-protein coupled receptor 139; Probable G-protein coupled receptor 139; probable G-protein coupled receptor 139; G protein-coupled receptor PGR3; G-protein-coupled receptor PGR3; g(q)-coupled orphan receptor GPRg1; G protein-coupled receptor 139; G(q)-coupled orphan receptor GPRg1; G-protein-coupled receptor PGR3
products gene name :
GPR139
other gene names :
GPR139; GPR139; PGR3; GPRg1; GPRG1; PGR3
uniprot entry name :
GP139_HUMAN
reactivity :
Gibbon, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat. Predicted Reactivity: Bovine, Chicken (at least 90% immunogen sequence identity)
specificity :
Human GPR139. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR142 (50%).
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (18 ug/ml)
other info1 :
Target Species: Human. Immunogen Description: Synthetic 16 amino acid peptide from 4th transmembrane domain of human GPR139. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Horse, Rabbit, Pig (100%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: GPR139 antibody was raised against synthetic 16 amino acid peptide from 4th transmembrane domain of human GPR139. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Horse, Rabbit, Pig (100%); Bovine, Opossum, Turkey, Chicken, Platypus (94%). Antigen Modification: Transmembrane Domain
products categories :
Family: GPCR. Subfamily: Orphan-U
products description :
The G protein-coupled receptor PGR3/GPR139/TGR20 is an Orphan-U GPCR with an unknown ligand.
ncbi acc num :
NP_001002911.1
ncbi gb acc num :
NM_001002911.2
ncbi mol weight :
40,679 Da
uniprot summary :
GPR139: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 16p12.3. Cellular Component: integral to membrane; plasma membrane. Molecular Function: protein dimerization activity; neuropeptide receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)