product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal (IgG) to Human PECAM-1 / CD31
catalog :
MBS242708
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS242708
products type :
Antibody
products full name :
Rabbit Polyclonal (IgG) to Human PECAM-1 / CD31
products short name :
PECAM-1 / CD31
products name syn :
Anti-PECAM-1 / CD31 Antibody (aa686-735) IHC-plus; PECAM1; CD31; CD31 antigen; EndoCAM; PECA1; PECAM-1; GPIIA; Human PECAM-1; CD31
other names :
platelet endothelial cell adhesion molecule; Platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule; CD31 antigen; platelet/endothelial cell adhesion molecule 1; EndoCAM; GPIIA'; PECA1; CD_antigen: CD31
products gene name :
PECAM-1
products gene name syn :
CD31
other gene names :
PECAM1; PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM; PECAM-1
uniprot entry name :
PECA1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
738
specificity :
PECAM-1 Antibody detects endogenous levels of total PECAM-1 protein.
purity :
Immunoaffinity Purified
form :
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
concentration :
1 mg/ml
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:20000), IF (1:100 - 1:500), IHC-P (10 ug/ml), WB (1:500 - 1:1000)
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human PECAM-1 (aa686-735).
other info2 :
Immunogen: PECAM-1 / CD31 antibody was raised against synthetic peptide from human PECAM-1 (aa686-735). Antigen Modification: aa686-735
products description :
CD31 (PECAM1) is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31 is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
ncbi gi num :
110347451
ncbi acc num :
NP_000433.3
ncbi gb acc num :
NM_000442.3
uniprot acc num :
P16284
ncbi mol weight :
81,378 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (106062); Extracellular Matrix Organization Pathway (576262); Hemostasis Pathway (106028); Integrin Cell Surface Interactions Pathway (106110); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Malaria Pathway (152665); Malaria Pathway (152657)
ncbi summary :
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
uniprot summary :
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 17q23.3. Cellular Component: extracellular space; platelet alpha granule membrane; integral to membrane; plasma membrane; cell junction. Molecular Function: protein binding. Biological Process: platelet activation; extracellular matrix organization and biogenesis; platelet degranulation; diapedesis; cell recognition; signal transduction; blood coagulation; cell adhesion; leukocyte migration; phagocytosis
size1 :
0.05 mg
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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