Rabbit Polyclonal (IgG) to Human GYPA / CD235a / Glycophorin A | MyBioSource MBS242698 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal (IgG) to Human GYPA / CD235a / Glycophorin A

catalog :

MBS242698

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS242698

products type :

Antibody

products full name :

Rabbit Polyclonal (IgG) to Human GYPA / CD235a / Glycophorin A

products short name :

GYPA / CD235a / Glycophorin A

products name syn :

Anti-GYPA / CD235a / Glycophorin A Antibody (N-Terminus) IHC-plus; GYPA; CD235a; CD235a antigen; Glycophorin A (MN blood group); Glycophorin A; GPA; Glycophorin-A; GPA; GPErik; GPSAT; Glycophorin MiV; Glycophorin SAT; HGpMiX; HGpMiXI; HGpMiV; HGpSta(C); Glycophorin MiI; GpMiIII; MN; HGpMiIII; MN sialoglycoprotein; Human GYPA; CD235a; Glycophorin A

other names :

glycophorin-A; Glycophorin-A; glycophorin-A; glycophorin MiI; glycophorin MiV; glycophorin SAT; glycophorin Erik; glycophorin A, GPA; MN sialoglycoprotein; glycophorin Sta type C; sialoglycoprotein alpha; Mi.V glycoprotein (24 AA); glycophorin A (MN blood group); recombinant glycophorin A-B Miltenberger-DR; erythroid-lineage-specific membrane sialoglycoprotein; glycophorin A (MNS blood group); MN sialoglycoprotein; PAS-2; Sialoglycoprotein alpha; CD_antigen: CD235a

products gene name :

GYPA

other gene names :

GYPA; GYPA; MN; GPA; MNS; GPSAT; PAS-2; CD235a; GPErik; HGpMiV; HGpMiXI; HGpSta(C); GPA

uniprot entry name :

GLPA_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

150

specificity :

Anti-human Glycophorin A (GpA) Polyclonal Antibody targets the human Glycophorin A protein. This 131 amino acid, 36 KDa, transmembrane sialoglycoprotein spans the membrane of erythrocytes once. GpA presents its N terminus at the extracellular surface of t.

purity :

Protein G Purified

form :

PBS, 0.02% sodium azide.

concentration :

1 mg/ml

storage stability :

Store at 4 degree C for short term applications. For long term storage, aliquot and store at -20 degree C.

tested application :

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Flow Cytometry (FC/FACS), ELISA (EIA)

app notes :

ELISA, Flo, IHC-P (5 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target Species: Human. Immunogen Description: Human Glycophorin A transmembrane protein.

other info2 :

Immunogen: GYPA / CD235a / Glycophorin A antibody was raised against human Glycophorin A transmembrane protein. Antigen Modification: N-Terminus

ncbi gi num :

75813628

ncbi acc num :

NP_002090.2

ncbi gb acc num :

NM_002099.4

uniprot acc num :

P02724

ncbi mol weight :

13,000 Da

ncbi pathways :

Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Malaria Pathway (152665); Malaria Pathway (152657)

ncbi summary :

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]

uniprot summary :

GYPA: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). Belongs to the glycophorin A family. Protein type: Membrane protein, integral; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 4q31.21. Cellular Component: membrane; integral to plasma membrane; plasma membrane; external side of plasma membrane. Molecular Function: viral receptor activity; identical protein binding; protein homodimerization activity. Biological Process: entry of virus into host cell; cytoskeletal anchoring; regulation of response to osmotic stress. Disease: Malaria, Susceptibility To

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage