Rabbit Polyclonal to Human LL37 / CAMP / Cathelicidin | MyBioSource MBS242692 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human LL37 / CAMP / Cathelicidin

catalog :

MBS242692

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS242692

products type :

Antibody

products full name :

Rabbit Polyclonal to Human LL37 / CAMP / Cathelicidin

products short name :

LL37 / CAMP / Cathelicidin

products name syn :

Anti-LL37 / CAMP / Cathelicidin Antibody (C-Terminus) IHC-plus; CAMP; Antibacterial protein fall-39; CAP-18; CRAMP; FALL-39; FALL39; HCAP-18; HSD26; LL37; CAP18; Human LL37; CAMP; Cathelicidin

other names :

cathelicidin antimicrobial peptide; Cathelicidin antimicrobial peptide; cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; CAP-18; hCAP-18

products gene name :

LL37

other gene names :

CAMP; CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39; CAP18; FALL39; CAP-18; hCAP-18

uniprot entry name :

CAMP_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human

sequence length :

170

purity :

Immunoaffinity Purified

form :

PBS, 0.02% sodium azide.

concentration :

1 mg/ml

storage stability :

Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

tested application :

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

app notes :

ELISA, IHC-P (5 ug/ml), WB (1 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target: LL37/Cathelicidin. Target Species: Human. Immunogen Description: 17 amino acid peptide near the carboxy terminus of the human Cathelicidin. Epitope: C-Terminus

other info2 :

Immunogen: LL37 / CAMP / Cathelicidin antibody was raised against 17 amino acid peptide near the carboxy terminus of the human Cathelicidin.

products description :

Immunohistochemistry: This Antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS242692 was determined to be 5 ug/ml.

ncbi gi num :

39753970

ncbi acc num :

NP_004336.2

ncbi gb acc num :

NM_004345.3

uniprot acc num :

P49913

ncbi pathways :

Disease Pathway (530764); Integrated Pancreatic Cancer Pathway (711360); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Phagosomal Maturation (early Endosomal Stage) Pathway (645268); SREBP Signalling Pathway (219802); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)

ncbi summary :

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

uniprot summary :

CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family. Protein type: Cell cycle regulation; Vesicle; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: extracellular space; specific granule; cell projection; cell wall; cytosol. Molecular Function: protein binding. Biological Process: interaction with host; defense response to Gram-positive bacterium; positive regulation of angiogenesis; innate immune response in mucosa; killing by host of symbiont cells; positive regulation of cell proliferation; defense response to bacterium; antibacterial humoral response; positive regulation of protein amino acid phosphorylation; defense response to Gram-negative bacterium

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage