catalog number :
MBS242641
products full name :
Rabbit Polyclonal to Human TAAR5
products short name :
TAAR5
products name syn :
Anti-TAAR5 Antibody (C-Terminus) IHC-plus; TAAR5; PNR; RP11-295F4.5; Trace amine receptor 5; TaR-5; Human TAAR5
other names :
trace amine-associated receptor 5; Trace amine-associated receptor 5; trace amine-associated receptor 5; taR-5; hTaar5; trace amine receptor 5; putative neurotransmitter receptor; trace amine associated receptor 5; Putative neurotransmitter receptor
products gene name :
TAAR5
other gene names :
TAAR5; TAAR5; PNR; PNR; TaR-5; Trace amine receptor 5; hTaar5
uniprot entry name :
TAAR5_HUMAN
reactivity :
Chimpanzee, Human. Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
specificity :
Human TAAR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes :
ELISA, IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubate.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 18 amino acid peptide from C-Terminus of human TAAR5. Percent identity with other species by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Gibbon, Baboon, Monkey (94%); Orangutan (89%); Marmoset, Tamarin (83%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: TAAR5 antibody was raised against synthetic 18 amino acid peptide from C-Terminus of human TAAR5. Percent identity with other species by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Gibbon, Baboon, Monkey (94%); Orangutan (89%); Marmoset, Tamarin (83%). Antigen Modification: C-Terminus
products categories :
Family: GPCR. Subfamily: Trace Amine Associated Receptor
products description :
TAAR5 is classified as an Orphan-A GPCR because the ligand has not been identified.
ncbi acc num :
NP_003958.2
ncbi gb acc num :
NM_003967.2
ncbi mol weight :
38,242 Da
ncbi pathways :
Amine Ligand-binding Receptors Pathway (106363); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Other Pathway (198765); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Neuroactive Ligand-receptor Interaction Pathway (83053)
uniprot summary :
TAAR5: Orphan receptor. Ligands are likely small molecules, either sharing some similarities with trace amine as, e.g. derivatives of indolamines (such as 5-methoxytryptamine) or of phenylethylamines (such as phenylethanolamine) or being any kind of metabolite of amino acids or biogenic amine neurotransmitters. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 6q23. Cellular Component: integral to plasma membrane; integral to membrane. Molecular Function: G-protein coupled receptor activity. Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; sensory perception of chemical stimulus; signal transduction