product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat Polyclonal to Human GPSM2 / LGN
catalog :
MBS242530
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, cow
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS242530
products type :
Antibody
products full name :
Goat Polyclonal to Human GPSM2 / LGN
products short name :
GPSM2 / LGN
products name syn :
Anti-GPSM2 / LGN Antibody (Internal) IHC-plus; GPSM2; DFNB82; LGN; PINS; CMCS; Mosaic protein LGN; Human GPSM2; LGN
other names :
G-protein-signaling modulator 2; G-protein-signaling modulator 2; G-protein-signaling modulator 2; mosaic protein LGN; G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein signaling modulator 2; Mosaic protein LGN
products gene name :
GPSM2
products gene name syn :
LGN
other gene names :
GPSM2; GPSM2; LGN; CMCS; PINS; DFNB82; LGN
uniprot entry name :
GPSM2_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Gibbon, Bovine, Human, Monkey. Predicted Reactivity: Dog (at least 90% immunogen sequence identity)
sequence length :
684
specificity :
Human GPSM2.
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:64000), IHC-P (5 ug/ml), WB (0.01 - 0.03 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-NRLKGKKYKTNSSTK from an internal region of human GPSM2 (NP_037428.2). Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Elephant, Bovine (100%); Dog (93%); Panda, Bat, Horse, Opossum, Platypus (87%); Hamster (80%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: GPSM2 / LGN antibody was raised against synthetic peptide C-NRLKGKKYKTNSSTK from an internal region of human GPSM2 (NP_037428.2). Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Elephant, Bovine (100%); Dog (93%); Panda, Bat, Horse, Opossum, Platypus (87%); Hamster (80%). Antigen Modification: Internal
ncbi gi num :
164519122
ncbi acc num :
NP_037428.3
ncbi gb acc num :
NM_013296.4
uniprot acc num :
P81274
ncbi mol weight :
76,662 Da
ncbi summary :
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).[provided by RefSeq, Jan 2011]
uniprot summary :
GPSM2: Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. Interacts with LLGL2. Interacts with INSC/inscuteable and probably with F2RL2. Ubiquitously expressed. Belongs to the GPSM family. Protein type: G protein regulator, misc. Chromosomal Location of Human Ortholog: 1p13.3. Cellular Component: apical part of cell; cytoplasm; cell cortex. Molecular Function: identical protein binding; protein binding; GTPase regulator activity. Biological Process: G-protein coupled receptor protein signaling pathway; establishment of mitotic spindle orientation; regulation of catalytic activity. Disease: Chudley-mccullough Syndrome
size1 :
0.05 mg
price1 :
495 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!