Rabbit Polyclonal to Human NT5E / eNT / CD73 | MyBioSource MBS242461 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human NT5E / eNT / CD73

catalog :

MBS242461

quantity :

0.2 mL

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS242461

products type :

Antibody

products full name :

Rabbit Polyclonal to Human NT5E / eNT / CD73

products short name :

NT5E / eNT / CD73

products name syn :

Anti-NT5E / eNT / CD73 Antibody (C-Terminus) IHC-plus; NT5E; 5-nucleotidase; ecto (CD73); 5'-nucleotidase; 5 nucleotidase (CD73); 5-NT; 5-nucleotidase; 5'-nucleotidase; ecto (CD73); CD73; CD73 antigen; E5NT; Ecto-5-nucleotidase; ENT; EN; NT; Purine 5-Prime-Nucleotidase; NT5; NTE; Human NT5E; eNT; CD73

other names :

5'-nucleotidase isoform 1 preproprotein; 5'-nucleotidase; 5'-nucleotidase; 5'-NT; ecto-5'-nucleotidase; Purine 5-Prime-Nucleotidase; 5'-nucleotidase, ecto (CD73); Ecto-5'-nucleotidase; CD_antigen: CD73

products gene name :

NT5E

products gene name syn :

eNT; CD73

other gene names :

NT5E; NT5E; NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA; NT5; NTE; 5'-NT

uniprot entry name :

5NTD_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse

sequence length :

574

specificity :

Cross-reactivity with mouse has been confirmed in WB only. The antibody has not been evaluated for use in IHC with mouse tissues at time.

purity :

Ammonium sulfate precipitation

form :

PBS, 0.09% sodium azide

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

tested application :

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

app notes :

IHC-P (10 ug/ml), WB (1:1000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target Species: Human. Immunogen Description: KLH conjugated synthetic peptide selected from the C-terminal region of human NT5E.

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: NT5E / eNT / CD73 antibody was raised against kLH conjugated synthetic peptide selected from the C-terminal region of human NT5E. Antigen Modification: C-Terminus

ncbi gi num :

4505467

ncbi acc num :

NP_002517.1

ncbi gb acc num :

NM_002526.3

uniprot acc num :

P21589

ncbi mol weight :

57,949 Da

ncbi pathways :

HIF-1-alpha Transcription Factor Network Pathway (138045); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Nucleotides Pathway (106263); Nicotinate And Nicotinamide Metabolism Pathway (83014); Nicotinate And Nicotinamide Metabolism Pathway (400); Purine Catabolism Pathway (106276); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (106265); Purine Metabolism Pathway (307)

ncbi summary :

The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

uniprot summary :

NT5E: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Homodimer; disulfide-linked. Belongs to the 5 -nucleotidase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor; Phosphatase (non-protein); Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; EC 3.1.3.5; Membrane protein, integral. Chromosomal Location of Human Ortholog: 6q14-q21. Cellular Component: cell surface; membrane; cytoplasm; plasma membrane. Molecular Function: 5 -nucleotidase activity; metal ion binding; nucleotide binding. Biological Process: pyrimidine nucleoside catabolic process; pyrimidine base metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; adenosine biosynthetic process; negative regulation of inflammatory response; purine nucleotide catabolic process; DNA metabolic process; purine base metabolic process; AMP catabolic process. Disease: Calcification Of Joints And Arteries

size1 :

0.2 mL

price1 :

495 USD

more info or order :

MyBioSource product webpage